PWAS Atlas: a comprehensive knowledgebase of proteome-wide association studies academic.oup.com/nar/article/.... 🧪 this resource manually curates protein-trait associations from published studies with harmonized PWAS results.

Real-space chemistry on quantum computers: a fault-tolerant algorithm with adaptive grids and a transcorrelated extension pubs.rsc.org/dd/article/d.... 🧪. Theoretical work employs multicenter grids, rooted in DFT which rarely exceed 105 points per atom. Researchers illustrate point on H2 simulation

Peer Bork (1963–2026): pioneer of computational biology, architect of bioinformatics resources, and visionary microbiome researcher academic.oup.com/bioinformati... a really great article on the impact of Peer and how he approached life.

journals.plos.org/plosone/arti.... Cool. Researchers demonstrate that FANS-isolated nuclei are compatible with a wide range of genomic assays, including profiling of DNA modifications, histone modifications, chromatin accessibility, and gene expression.

The unfolded protein response in precision oncology: from mechanisms to therapeutic opportunities: Trends in Molecular Medicine www.cell.com/trends/molec.... 🧪 interesting article on Single-cell and spatial transcriptomics to provide dynamic, multigenic unfolded protein response signatures.

User Beware: Inaccuracy and Inconsistency of Large Language Models in Providing Precision Dosing Recommendations for Patients With Kidney Impairment—A Case Series - Hambrick - 2026 - Pharmacotherapy accpjournals.onlinelibrary.wiley.com/doi/10.1002/... 🧪

www.nature.com/articles/s41... 🧪. Interesting conceptual design for a fault-tolerant photonic quantum computer.

www.nature.com/articles/s41... 🧪

link.springer.com/article/10.1.... 🧪

Short‐Term Dietary Intervention Alters Physiological Profiles Relevant to Ageing - Andrews - 2026 - Aging Cell - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/... 🧪 study finds balanced diet rich in complex carbohydrates, derived minimally processed sources yield positive results

www.nature.com/articles/s41... 🧪 just out. Includes a AD-phenotypic single-cell atlas and a framework with open-source tools and pre-trained models

Convex approaches to isolate the shared and distinct genetic components of complex traits academic.oup.com/bioinformati.... Nice work breaking the Z score matrix as a sum of 2 components: a low-rank matrix of shared genetic signal across traits & a sparse matrix
representing trait-specific effects🧪

link.springer.com/article/10.1.... Improved methods provides lower false positives and negative rates. 🧪

Artificial intelligence for Amazonian health: validation is the price of entry - The Lancet Regional Health – Americas www.thelancet.com/journals/lan... 🧪 great read. Makes the point health “innovations deliver optimal results when governance and execution are rooted locally”

Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/... neat article that explains how biocatalysis went from niche to a core capability through high-throughput screening, directed evolution, and process development.

mentalhealth.bmj.com/content/29/1... highest risk occurred during the unexposed period immediately before starting treatment. The findings across various health systems do not support ADHD medications as the main driver of self-harm.

How Repeal of the NTAP Alternative Pathway will Impact U.S. Clinical AI Innovation | NEJM AI ai.nejm.org/doi/full/10....

The elimination of the NTAP alternative pathway will disadvantage independent developers and researchers.

link.springer.com/article/10.1.... 🧪 nice work

link.springer.com/article/10.1... 🧪. Interesting work examining dynamic and common regulatory pathways across different disease states.

Longitudinal dynamics of gene expression and metabolomics in an aging population cohort | Science www.science.org/doi/10.1126/... study illustrating which genes & metabolites change over time; how much individuals diverge from populations and how trajectories are shaped by intrinsic factors