New tool in the breast cancer toolbox: eRNACare, a public web application for individualized survival and tumor probability scoring based on validated panels of enhancer RNAs. New in NAR Cancer. academic.oup.com/narcancer/ar...
Bill Dynan - NAR Cancer Editor
@nar-cancer-editor.bsky.social
Editor of fully Open Access journal publishing articles at the intersection of the nucleic acids research and cancer fields.
From Dmitry Gordenin and colleagues: Half of tumor mutations may accumulate while precancer, but study is challenging. Analysis of 10,000 human samples identifies mutations arising from clock-like processes, deaminases, mutagens. Fundamental + practical insights. 3/3 academic.oup.com/narcancer/ar...
From Bevin Engelward and colleagues: Spectacular study of NDMA liver carcinogenesis in mice shows persistent adducts, DNA damage response, interferon expression, immune cell infiltration, and clonal expansion promoting tumor emergence. Destined to be a classic! 2/3 academic.oup.com/narcancer/ar...
First articles published in NAR Cancer 2026 Collection: Seeds of Cancer, Decades of Silence: Ageing and Environmental Control of Tumor Latency. Cancer risk can originate early in life, yet malignancy often emerges decades later. Let's explore that latency! 1/3
Glioblastoma remains one of the most feared cancers. Here, in vivo-selected, shape-based DNA aptamers are used to replace the large antibodies used in conventional drug conjugates - unbiased approach to a problem that rational design has yet to overcome. academic.oup.com/narcancer/ar...
Ewing sarcoma tumor fitness depends on three snoRNA host genes–SNHG1, SNHG12, and SNHG30–that regulate chemical modification of ribosomal RNA. Blocking them slowed tumor growth, pointing to a strategy to target the unique EWS-FLI1 biology sustaining Ewing sarcoma. academic.oup.com/narcancer/ar...
