As a reminder, Symptom Saturday is our ongoing series that has been running over the past two months, dedicated to exploring core and additional symptoms of ME/CFS to help further understanding of this profoundly debilitating disease.

Keep up to date with the series: tinyurl.com/symptomsatur...

ME/CFS-related fatigue is not everyday tiredness, nor is it normal fatigue experienced by healthy people. It is a crushing symptom felt throughout the entire body.

For Symptom Saturday, we drew together some of the common themes about the experience of fatigue: tinyurl.com/fatigueimpac...

ME Research UK Christmas cards are now on sale. All profits aid our work.

Full Details - tinyurl.com/3fdu9xac

ME Research UK has published articles reflecting on ISLC-PAIS 2026.

1: Highlights from ME Research UK–funded projects (tinyurl.com/246rj47b)
2: Systems thinking, terminology, and negative trials (tinyurl.com/2fw5rt95)
3: What worked well and areas for further consideration. (bit.ly/4dgOAU6)

@bsky.app ME Research UK's September e-newsletter has been sent to all on our mailing list.

Also available on our website - tinyurl.com/yvnety7y - but why not sign-up to receive new issues directly? - tinyurl.com/mr45azsf

October is Dysautonomia Awareness Month. Dysautonomia encompasses conditions that affect the autonomic nervous system, e.g. orthostatic intolerance (including PoTS), and can significantly impact quality of life. People with ME/CFS often report related symptoms.
tinyurl.com/dysauto2026

In the fourth deep-dive of our weekly Symptom Saturday series, we explored debilitating fatigue in ME/CFS – including lived experience, research insights, related diagnostic delays, and management.

Read more: tinyurl.com/fatiguesympt...

Survey: tinyurl.com/fatiguesurve...

In case you missed it -
Sleep dysfunction can feel like a heavy weight on top of an already debilitating condition. We have drawn together some of the common themes about the experience of sleep dysfunction from our recent survey.
tinyurl.com/sleepdysmeim...

In the third deep-dive of our Symptom Saturday series, we explored sleep dysfunction in ME/CFS – including lived experience, patterns of sleep disruption, and research suggesting challenges across the brain and nervous system. tinyurl.com/sleepdyssymp...

Survey: tinyurl.com/sleepdyssurv...

Cognitive dysfunction is an intense, deeply distressing symptom that can erode many aspects of life. Careers are impacted, hobbies become exhausting or impossible, and relationships grow strained under the weight of this symptom.

tinyurl.com/brainfogimpa...

In the second deep-dive of our weekly Symptom Saturday series, we unpacked the reality of cognitive dysfunction in ME/CFS – including lived experience, key insights from research spanning interconnected body systems, and comorbidities. tinyurl.com/brainfogsymp...

Survey: tinyurl.com/brainfogsurv...