Excited to share our work reporting that fly Lsp2 acts as a nutrient-induced physiological factor that amplifies mTORC1 output in TOP mRNA translation and regulates lifespan.
www.nature.com/articles/s41...
@obataf-lab.bsky.socialThanks, Helena!
Fumiaki Obata
@obataf-lab.bsky.social
PI studying nutritional biology at RIKEN Center for Biosystems Dynamics Research & visiting associate professor in Kyoto University. Interested in Drosophila genetics, amino acid, nutrient, microbiota, metabolism, ageing, lifespan, and many others
@obataf-lab.bsky.social@obataf-lab.bsky.socialThanks!
@immuno-physiology.bsky.socialReposted by @obataf-lab.bsky.social
@nature.comReposted by @obataf-lab.bsky.socialA fruit-fly protein thought only to store amino acids in fact responds to nutritional deficiency in both development and adulthood, resulting in lifespan extension
@obataf-lab.bsky.socialVery nice News&Views by Linda Partridge for our paper and the back-to-back study by Zhai's group. Thanks everyone involved!
www.nature.com/articles/d41...
www.nature.com/articles/s41...
@obataf-lab.bsky.socialOur new study just out @nature.com Together with Koshi Imami @RIKEN IMS, Hina Kosakamoto found out the key molecule mediating lifespan extension by early life dietary restriction! www.nature.com/articles/s41...