The Pediatric Cancer collection highlights impactful findings that provide insight into fundamental cancer biology, identify novel cancer therapeutics, and lead to new therapies for a patient population that faces significant barriers to meaningful progress. Read more: buff.ly/Lx8DRrK
Tremendous progress has been made in elucidating and targeting the biological mechanisms driving pediatric cancers, resulting in the increase of 5-year survival rates for all pediatric cancers. However, pediatric cancers remain one of the leading causes of childhood mortality overall.
➡️Then, read the related commentary: The Modular CAR: Adapting T Cells without Reengineering Them buff.ly/fcN3TdD
From the October issue of Cancer Immunology Research: Meditope-Enabled Chimeric Antigen Receptors Facilitate Plug-and-Play Control of T Cells buff.ly/pGhnab6
Read: "A Patient-Derived Xenograft Repository Capturing Clinical and Molecular Heterogeneity of Large B-cell Lymphoma" from the most recent issue of Blood Cancer Discovery. buff.ly/slTD8hG
From the October issue of Molecular Cancer Research: ERG Orchestrates a Dedifferentiation–Senescence–Inflammation Triad in Prostate Cancer
➡️Read the article: buff.ly/WXC7pIF
Read the article, just published in Cancer Discovery: Universal Germline Genetic Testing after a Diagnosis of Cancerhttps://doi.org/10.1158/2159-8290.CD-26-0971
➡️Don't miss the related commentary: Active Surveillance for Atypical Ductal Hyperplasia: Are We Ready for Surgical De-escalation? buff.ly/d9ukXYT
From the October issue of Cancer Prevention Research: Active Monitoring versus Surgical Excision for Atypical Ductal Hyperplasia buff.ly/5OCB20P
Read: "CAR T Cells Targeting an Intracellular Leukemia Antigen Promiscuously Presented by Diverse HLA-II Alleles" from the most recent issue of Blood Cancer Discovery. buff.ly/kd6Qm4e
The Researchers Behind the AACR Journals
Watch our interview with Charles L.H. Earnshaw, PhD, MA, MB, BChir.
Dr. Earnshaw shares the story of his recently published Cancer Discovery study, his advice for the cancer research community, and more! buff.ly/rnCg1js
Read the article: buff.ly/xLUXrlx
The November 6 submission deadline for the inaugural Cancer Immunology Research Early Career Award is fast approaching. Do you have a question about the nomination process? Contact us at [email protected]. buff.ly/S4S2GwE
I-Mei Siu, PhD, Senior Editor of Cancer Discovery, is excited to meet with the community at The Sixth RAS Initiative Symposium. If you have a question about the AACR Journals or are interested in discussing your research, reach out to her at [email protected].
Read the October issue of Molecular Cancer Therapeutics: buff.ly/eTNBaNT
Read the October issue of Cancer Immunology Research: buff.ly/kZtGSKv
From Clinical Cancer Research: Zanidatamab + Tislelizumab + Chemo in 1L HER2+ Gastric Cancer/GEJC doi.org/10.1158/1078...
From Cancer Discovery: Sevabertinib for HER2 Alterations in Lung Cancer doi.org/10.1158/2159...
From Molecular Cancer Therapeutics: Zidesamtinib Inhibits Diverse ROS1 Drug-Resistant Mutants doi.org/10.1158/1535...
From Cancer Research: Imlunestrant in ESR1 Wild-Type and Mutant Breast Cancer doi.org/10.1158/0008...
Read related studies from the AACR Journals 👇
