ADA Professional Publications

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Diabetes, Diabetes Care, Diabetes, Obesity & CardioMetabolic Care, books & podcasts—are leading sources on diabetes research, care, prevention & treatment.

@adapubs.bsky.social Oct 10, 2026, 6:55 PM

Research shows mtDNA deletions cause 3% of unresolved syndromic diabetes. Routine screening via existing WGS data is recommended to increase diagnostic yield for free.

Read here ➡️ doi.org/10.2337/dc26-1211

Diagram representing human mitochondrial DNA (mtDNA). It features a circular map with sections labeled for control region, polypeptides, transfer RNA, and ribosomal RNA. Key genetic markers like MT-CYB, MT-ND1, MT-ND5, and MT-ND6 are indicated, along with amino acids and structural regions on L and H strands. Arcs depict overlapping gene regions.

@adapubs.bsky.social Oct 9, 2026, 8:45 PM

Microgel technology could offer a more favorable risk-benefit profile by reducing infection risks, organ toxicity, and tumorgenicity associated with the use of systemic immunosuppression.

Read here ➡️ doi.org/10.2337/db26-0280

Diagram illustrating a scientific process to enhance islet function and viability. The left section shows prosurvival molecules and immunomodulatory properties, leading to recruitment of T regulatory cells. The middle section features engineered microgels with SA-protein protecting co-transplanted islets. The right section depicts the reduction of cytotoxic T cells and increase in T regulatory cells, highlighting improved islet function. Arrows indicate the flow of the process across the sections.

@adapubs.bsky.social Oct 9, 2026, 6:10 PM

Weekly blood ketone tests over one month can predict DKA risk in next month as accurately as twice-weekly checks. This approach reduces testing burden while maintaining clinical predictive power.

Read here ➡️ doi.org/10.2337/dc26-1110

This image is a research poster titled "The Minimum Frequency of Well-Day Capillary Blood Ketone Testing Needed to Predict 1-Month Diabetic Ketoacidosis Risk in Type 1 Diabetes." It contains four sections: Aim, Study Population, Results, and Implications. The Aim notes the investigation of blood ketone testing frequency for predicting diabetic ketoacidosis risk. The Study Population uses data from EASE 2 and 3 trials with 1,410 participants. Results are shown in a graph, indicating that biweekly ketone testing matches the predictive accuracy of daily testing. The Implications suggest that less frequent testing can potentially enhance adherence without reducing performance.

@adapubs.bsky.social Oct 9, 2026, 2:00 PM

🚨 New journal, new #podcast. The Points of CARE covers highlights in each issue of DOCM CARE.

🎧 thepointsofcare.libsyn.com
📚 diabetesjournals.org/docm-care

In this ep:
✨ Variability in Autoantibody Ordering Patterns
✨Cognitive Change in Older Adults With T1D
✨& more!

@adapubs.bsky.social Oct 8, 2026, 10:20 PM

This scientific statement supports diabetes technology use in the primary care setting. Team-based models and virtual support can expand access and advance equitable diabetes care.

Read here ➡️ doi.org/10.2337/doci26-0005

Diagram illustrating steps to integrate diabetes technology into primary care. It starts with designating a diabetes technology champion, then assessing team capacity. Based on the assessment, options include training existing team, leveraging a trained interdisciplinary team, or referring to external resources. Ends with diabetes technology integration into primary care.

@adapubs.bsky.social Oct 8, 2026, 7:25 PM

#DiGest Follow-Up: In #GDM, late-pregnancy energy restriction or modest weight loss showed no harm to infant growth to 1 year, and weight loss was linked to lower LGA risk and fat mass at 3 months.

Read here ➡️ doi.org/10.2337/dc26-0405

The image is an infographic titled "DiGest: the Follow-up Study," supported by Diabetes UK. It is divided into three sections: Methods, Results, and Conclusions. 1. Methods: A study involving 425 pregnant individuals with gestational diabetes and pre‑pregnancy BMI ≥ 25 kg/m². They were randomized into two groups: reduced energy (1,200 kcal/day) and standard energy (2,000 kcal/day). 2. Results: Highlights findings on weight loss during pregnancy and its effects on maternal and infant outcomes. Weight loss was associated with lower maternal weight at 3 months, but not at 12 months postpartum. Infant weight was not affected at 2 months postpartum. 3. Conclusions: Suggests energy restriction or modest weight loss in pregnancy did not affect the infant’s growth or the likelihood of growth abnormalities in early life.

@adapubs.bsky.social Oct 8, 2026, 7:15 PM

👀 The latest issue of Diabetes, Obesity, and CardioMetabolic CARE (DOCM CARE), the new ADA journal focused on comprehensive, person-centered care, is live.

🔗 http://diabetesjournals.org/docm-care

Featuring:
✨ Cognitive Change & T1D
✨ School Meals & Prediabetes
✨ & more!

The Sept/Oct DOCM cover, featuring digital art, "Individuation," by Linda Kramer.

@adapubs.bsky.social Oct 7, 2026, 6:35 PM

This retrospective study found that excess risk of mortality, cardiovascular events, and end-stage kidney disease was lower with older ages at #T1D diagnosis.

Read here ➡️ doi.org/10.2337/dc26-0200

This infographic presents a study on type 1 diabetes, examining how age at diagnosis affects mortality and complications. The context section explains it used data from the Swedish National Diabetes Register, focusing on mortality and cardiovascular and kidney outcomes. The key findings section shows that each 1-year increase in diagnosis age lowers mortality risk by 1.7%, with specific reductions in acute myocardial infarction, heart failure, diabetic nephropathy, and end-stage kidney disease.

@adapubs.bsky.social Oct 7, 2026, 3:05 PM

Adherence to Life’s Essential 8 is associated with a lower risk for mild cognitive impairment and dementia in people with diabetes, even accounting for genetic risk.

Read here ➡️ doi.org/10.2337/dc25-3126

Infographic titled "The Joint Effects of Life’s Essential 8 and Genetics on Mild Cognitive Impairment and Dementia Risk in People With Diabetes." It includes a pie chart showing percentages of diabetes prevalence across different ethnicity groups. Methods include various health metrics and genetic risk scores. Key findings highlight the association between Life's Essential 8 (LE8), cognitive health, and brain structure alterations. An objective and conclusion summarize the study's focus and outcomes.

@adapubs.bsky.social Oct 6, 2026, 8:45 PM

Among older adults with longstanding #T1D, nearly two-thirds had intermediate or greater risk of obstructive sleep apnea and over 40% reported poor sleep quality. 😴

Read here ➡️ https://doi.org/10.2337/dc26-1678

The image is an infographic about the increased risks of poor sleep quality and excessive daytime sleepiness among older adults with Type 1 Diabetes. It displays data from the DCCT/EDIC study of 963 adults aged 48 to 79, where 67% had intermediate or greater OSA risk, 43% had poor sleep quality, and 22% experienced excessive daytime sleepiness. For each 1% increase in HbA1c, the risk of sleep-related problems reportedly increased by 15-20% for current and 40-year mean exposure, adjusted for age, sex, and BMI. Further assessments and objective measures of sleep-related problems are warranted due to many unrecognized cases.

@adapubs.bsky.social Oct 6, 2026, 7:00 PM

Central PDE4 inhibition promotes brown adipose tissue thermogenic activity and contributes to the metabolic effects of rolipram.

Read here ➡️ doi.org/10.2337/db25-1135

A diagram illustrates a scientific experiment. A mouse is depicted connected via a tube to a syringe labeled "Rolipram." The mouse's brain and brown adipose tissue are highlighted. The brain's phosphodiesterase 4 is marked, indicating a pathway to increased UCP1, temperature, and energy expenditure. Another syringe is labeled "YM-976.

@adapubs.bsky.social Oct 6, 2026, 2:18 PM

🚨 NEW DOC Updates #podcast

You know how GLP-1s impact diabetes & weight loss. But what about coronary disease treatment? Liver disease? Heart failure? In this special ep, we explores the latest in incretin biology.

👂Listen: diabetesjournals.org/journals/pages/podcasts_incretin_biology

@adapubs.bsky.social Oct 6, 2026, 11:50 AM

HTD1801, a first-in-class, novel therapy, significantly reduced HbA1c and improved cardiometabolic and inflammatory markers in participants with #T2D.

Read here ➡️ doi.org/10.2337/dc26-0739

The image is an infographic detailing the effects of HTD1801 on type 2 diabetes markers. It includes sections on objective, study design, results, and conclusion. A graph shows a decrease in HbA1c levels over time. Key measurements include glucose metabolism (HbA1c, FPG), lipid metabolism (non-HDL-c), and inflammation (hs-CRP). The study utilized a randomized, placebo-controlled method.

@adapubs.bsky.social Oct 5, 2026, 8:47 PM

🚨 New for Oct, the latest #DiabetesBio #podcast!

In this episode:
✨ GIP & Muscle Microvascular Perfusion
✨ Adipose Tissue Palmitoylation & Insulin Resistance
✨ Plus "Sweet Talk" with Michael Schwartz

🎙️Listen: http://diabetesbio.libsyn.com
📚Read: http://diabetesjournals.org/diabetes/issue/75/10

@adapubs.bsky.social Oct 5, 2026, 6:55 PM

In this study, PCOS was associated with increased early GDM, and adverse neonatal outcomes, underlining importance of identification, monitoring and treatment of PCOS.

Read here ➡️ doi.org/10.2337/dc25-1704

Institutional infographic explaining a study on maternal and neonatal complications in pregnancy with Polycystic Ovarian Syndrome (PCOS). Sections include objectives, design and methods, results, and conclusion. Data visualized in charts indicates increased risks in pregnancies with PCOS, detailing outcomes and gestational age impacts. Concludes by comparing risks with other conditions and advising early identification of PCOS.

@adapubs.bsky.social Oct 5, 2026, 6:15 PM

Findings support the use of autoantibody screening and genetic testing of autoantibody negative patients as standard of care for #T1D.

Read here ➡️ doi.org/10.2337/db25-1110

The image is an infographic titled "What Proportion of Antibody-Negative Type 1 Diabetes Cases Have a Nonautoimmune Etiology? A Genetics-Based Estimate." It includes sections on background, methodology, and conclusions, with a central graph showing the distribution of GRiD2 scores among various groups, including those with unknown cause and controls. The graph features a probability density curve with different shaded regions representing the groups. The infographic includes panels detailing affected siblings in the genetics consortium study. Key terms are highlighted in blue boxes, and the image concludes that a portion of diagnosed antibody-negative Type 1 diabetes cases may have nonautoimmune causes.

@adapubs.bsky.social Oct 5, 2026, 12:45 AM

Facing an acute diabetes burden, Asia is advancing solutions: optimizing medicines, developing novel agents, and maturing technologies, contributing to global glucose-lowering treatment innovation.

Read here ➡️ doi.org/10.2337/dci26-0057

Infographic titled "Asia's Ascension in Diabetes Innovation: From Adopter to Architect." It features four main sections: "Context & Drivers," "Comprehensive Review: Dynamic Innovation Landscape," "Synthesis & Future Trajectory," and a side bubble on evolving contribution. Key elements include R&D investment, new biological insights, emerging target exploration, and frontier technologies like AI and stem cells. A flow chart highlights progression from delivery of sustained-release agents to global innovation leadership. Icons and arrows illustrate steps and connections within the innovation process.

@adapubs.bsky.social Oct 4, 2026, 8:00 PM

We leveraged CGM data within a robust sample of adults without diabetes to uncover the heterogeneity in dysglycemia and cardiometabolic risk that are otherwise not captured by traditional measures.

Read here ➡️ doi.org/10.2337/dc26-1197

This image is a scientific chart titled "Beyond Traditional Glycemic Measures: CGM Glycemic Profiles Reveal Associations With Cardiometabolic Risk in Individuals Without Diabetes." It features multiple graphs and a radar chart comparing different glycemic profiles. The graphs show data on CGM glycemic burden and variability across different profiles. The radar chart includes metrics like fasting glucose, triglycerides, and more. The background is white with red and grey text and graphics.

@adapubs.bsky.social Oct 4, 2026, 2:00 PM

Time restricted eating is feasible and safe in new-onset type 1 diabetes, and may be efficacious in preserving beta-cell function in those with a higher BMI.

Read here ➡️ doi.org/10.2337/doc25-0087

This image is an infographic titled "Time-Restricted Eating (TRE) in Youth With Type 1 Diabetes (T1D)." It shows a line graph with glucose values over time, including two lines for baseline and TRE. Baseline fluctuates higher than TRE. A shaded area represents the eating window from noon to 8 p.m. Summary text on the right explains that over 8 weeks, participants aged 12‑25 fasted for 16 hours daily. Results indicate improvements in C‑peptide AUC, HbA1c, and lack of adverse events. Subgroups based on BMI are shown with different percentage changes. The conclusion states TRE is feasible and safe for youth with T1D.

@adapubs.bsky.social Oct 3, 2026, 10:00 PM

Structured quality improvement initiative was associated with improvements in obesity care processes and weight outcomes, supporting the feasibility of scalable continuing medical education, workflow, and patient engagement tools..

Read here ➡️ https://doi.org/10.2337/doc26-0041

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