Using Bayesian variable selection, QTL mapping, and context-dependent mediation analysis, researchers dissected genetic regulation of immune traits and their contribution to #COVID-19 disease severity in mice 🐭.

Now live in the October issue of #GENETICS: 🔗 buff.ly/QVSTjpc

📣 Attention all educators!

The latest Primers published in #GENETICS in 2026 cover mitochondrial protein cleanup, epigenetic inheritance, neuronal lipids, and QTL mapping. Explore these resources for bringing genetics concepts into the classroom: buff.ly/UKcDiR4

🪰 Discover the latest #Drosophila transcriptome in the October issue of #GENETICS

It provides a high-resolution view of larval transcriptional regulation under normal and parasitic wasp–infested conditions, highlighting the roles of noncoding RNAs in innate immunity.

🔗 buff.ly/PBqbEvG

🪰 Copulatory wounds are injuries that arise during mating in insects.

The October issue of #GENETICS features a #Drosophila model of copulatory wounds and their healing, offering a genetic system to study sexual conflict in the animal kingdom.

🔗 buff.ly/6YNlA89

📷️ Sophie Jalkut & Vicki Losick

Know an outstanding early career Drosophila neurogenetics researcher? Nominate them for the Hugo Bellen and Catherine Tasnier Drosophila Neurogenetics Lecture for #Dros27! Nominations close October 22. 🔗: buff.ly/I9LQcdS

📖 Want to learn about QTL mapping?

Shizhong Xu's primer unpacks the basics of QTL mapping with the goal of making it accessible to audiences with limited statistical and genetic knowledge.

Read more in October's #GENETICS issue: 🔗 buff.ly/RnpdAyS

New in #G3journal: A comparative analysis of histone organization in #yeast Ogataea polymorpha (used for industrial protein production) and O. haglerorum reveals new signatures, highlighting genome function differences occurring on a microevolutionary scale.

🔗 buff.ly/C2ZNE8M

A biochemical approach identifies Ypk2 in the pathogenic #yeast Candida glabrate plays an important role in coordinating gene expression that impacts susceptibility to all major #antifungal drug classes.

Learn more in #GENETICS 🔗 buff.ly/0mDxVJW

Cryptic peroxisomal targeting determinants in protistan glycolytic enzymes suggest how glycosomes may have evolved.

Find out more in #GENETICS 🔗 buff.ly/aVdSO96

🚨 LMAP starts soon! Bioscience grad students and postdocs: join us at 3 p.m. EDT, October 15, for the first session of this 6-week leadership & management program. It’s not too late to apply if space remains! 🔗 buff.ly/CLIHg0d

If all spaces are filled, you'll be added to a waitlist.

A population genetics study investigates how genetic variation is maintained in a polygenic trait under stabilizing selection in a subdivided population.

Learn more in #GENETICS 🔗 buff.ly/cDuTqm4

New experiments in REV1-deficient #yeast cell lines assess whether the preferential use of the error-prone repair pathway by haploids explains the difference in genome-wide mutation patterns between diploids and haploids.

Read more in #GENETICS 🔗 buff.ly/4llBZ8b

🪰 New in #GENETICS: @rajitha91.bsky.social et al. present a gene regulatory network that controls Abd-B expression in #Drosophila larval fat body and provide a molecular mechanism for establishing adipocyte heterogeneity along the anterior–posterior axis.

🔗 buff.ly/QJ2kVhS

📣 Call for papers!

#GENETICS and #G3Journal invite original research on new methods for improving crop and ornamental plants, including genomic prediction, phenomics, breeding program design, and genome editing.

⏰ Papers are due January 18, 2027.

🌱: buff.ly/HIkVPqQ

A new study in #GENETICS critically examines the feasibility of reconstructing lineage trees from single-cell transcriptomic data using both modeling and empirical data.

TL;DR: Gene expression data have limited potential and should not be used for phylogenetic lineage tree.
🔗 buff.ly/Y9f3lhh

The #G3journal cover shows a ZEISS UltraPlus FESEM image with myrtle rust spores (yellow) bursting out of a Syzygium jambos leaf (green) by tearing through the epidermis (Luo Z et al. jkaf255). Read the issue online: buff.ly/UcqPaWL

📸: Lavi Singh

The October #GENETICS cover, inspired by Warli tribal art from Maharashtra, India, illustrates the newly identified glycolysis–calcineurin regulatory axis governing titan cell formation in Cryptococcus neoformans (iyag211).

🔗: buff.ly/HsskEu6

🎨: Anandi Singh, Pallavi S. Phatak, and Sriram Varahan

New in #GENETICS: A mutant analysis in Saccharomyces cerevisiae demonstrates that replication defects generating single-stranded DNA (ssDNA) caused by the downregulation of the major replicative polymerases results in elevated formaldehyde mutagenesis.

🔗 buff.ly/SniUrU5

🧬 Dive into the perspective article in #GENETICS that proposes investigating the genetic architecture of complex phenotypes in lower-risk, younger individuals, which may reduce residual variance and improve power to isolate the genetics of complex disease-related traits.

🔗 buff.ly/M3WFZ05

Applications are open for the Drosophila Trainee Award! Graduate students and postdocs can request up to $1,000 in travel support to attend #Dros27. GSA membership required. Apply by October 29: buff.ly/Ceok9ob