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Yun S. Song

@yun-s-song.bsky.social

128 Following928 Followers

Professor of EECS and Statistics at UC Berkeley. Mathematical and computational biologist.

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@yun-s-song.bsky.socialSep 26, 2026, 6:09 PM

This is a broad, open-area search in AI for Biology. We are seeking candidates who develop innovative AI and machine learning (ML) methods that significantly advance our understanding of complex biological systems and address high-impact problems in biology.

@yun-s-song.bsky.socialSep 26, 2026, 6:09 PM

This is a joint search between the Department of Electrical Engineering & Computer Sciences (EECS) and the Center for Computational Biology (CCB). We encourage applicants with ambitious research programs at the interface of AI, computing, and biology to apply.

@yun-s-song.bsky.socialSep 26, 2026, 6:09 PM

We are excited to announce a new faculty position in AI for Biology at UC Berkeley.

Please repost & share this opportunity with outstanding early-career researchers in your networks.

Apply by Nov 9, 2026: aprecruit.berkeley.edu/JPF05560

@yun-s-song.bsky.socialSep 23, 2026, 6:18 PM

We welcome outstanding candidates from AI/ML, computer science, statistics, mathematics, and related quantitative fields who are excited to develop innovative computational methods and apply them to important problems in biology and medicine. (n/n)

@yun-s-song.bsky.socialSep 23, 2026, 6:18 PM

BCBI offers a distinctive model for postdoctoral research that fosters scientific independence, interdisciplinary collaboration, and close engagement with important problems in biology and medicine. (2/n)

@yun-s-song.bsky.socialSep 23, 2026, 6:18 PM

Please help spread the word! We are recruiting multiple Postdoctoral Fellows as part of the recently launched Bakar Computational Biomedicine Initiative (BCBI) at UC Berkeley and UCSF.

BCBI website: bcbi.berkeley.edu
Apply by Nov 1, 2026: berkeley.infoready4.com#freeformComp...
(1/n)

@yun-s-song.bsky.socialSep 9, 2026, 5:46 PM

We hope these models, predictions, and datasets will be useful to the genomics community. Please check out the paper and resources above. For more background on GPN-Star, see my earlier post: bsky.app/profile/yun-...
(n/n)

@yun-s-song.bsky.socialSep 9, 2026, 5:46 PM

This work was led by my talented students
@czye.bsky.social and @gonzalobenegas.bsky.social sky.social, with contributions from other members of our lab (Carlos Albors, Canal Li, and Sebastian Prillo), @peterdfields.bsky.social lds.bsky.social
at JAX, and @brianfclarke.bsky.social at DKFZ.
(5/n)

@yun-s-song.bsky.socialSep 9, 2026, 5:46 PM

The pretrained models, training datasets, and benchmark datasets are also available on Hugging Face: huggingface.co/collections/...
(4/n)

@yun-s-song.bsky.socialSep 9, 2026, 5:46 PM

Precomputed GPN-Star predictions for all possible single-nucleotide variants in the human genome and five model organisms (Mus musculus, Gallus gallus, Drosophila melanogaster, Caenorhabditis elegans, and Arabidopsis thaliana) are available on Hugging Face: doi.org/10.57967/hf/...
(3/n)

@yun-s-song.bsky.socialSep 9, 2026, 5:46 PM

The published version has a new title, “Predicting genome-wide functional constraints with GPN-Star,” and, more importantly, includes a substantial number of new results not present in the original preprint, with 16 additional figures. (2/n)

@yun-s-song.bsky.socialSep 9, 2026, 5:46 PM

We are thrilled to share that our GPN-Star manuscript is now published and freely available: doi.org/10.1038/s415...
(1/n)

@yun-s-song.bsky.socialJul 6, 2026, 6:33 PM

I am thrilled to share that UC Berkeley and UCSF have launched a joint initiative in Computational Biomedicine!
cdss.berkeley.edu/news/uc-berk...

We will soon be recruiting new faculty and postdoctoral fellows. Please repost to help spread the word.

cdss.berkeley.eduUC Berkeley and UCSF Launch Computational Biomedicine InitiativeUC Berkeley and UCSF have launched a joint program called the Bakar Computational Biomedicine Initiative to develop the frontier of AI and biomedicine, tremendously accelerating advances in clinical c...
3
@yun-s-song.bsky.socialMay 23, 2025, 9:02 PM

How can one efficiently simulate phylodynamics for populations with billions of individuals, as is typical in many applications, e.g., viral evolution and cancer genomics? In this work with M. Celentano, @wsdewitt.github.io , & S. Prillo, we provide a solution. doi.org/10.1073/pnas...
1/n

WWilliam DeWitt@wsdewitt.github.ioMay 21, 2025, 2:27 AM

Recasting the perils of phylodynamic non-identifiability as a feature not a bug, we show that a unique forward-equivalent process enables exact and efficient simulation from arbitrarily large populations. With M Celentano, S Prillo, @yun-s-song.bsky.social www.pnas.org/doi/10.1073/pnas.2412978122

A full lineage tree and it's corresponding ascertained treeTree conditioned on survival is equal in law to an unconditioned tree with modified parameters
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