Bottlenecks in the study of TCR-antigen specificity:
@natmethods.nature.comNature Methods
@natmethods.nature.com
A scientific journal publishing cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Posts by the editors.
@natmethods.nature.com@natmethods.nature.comStewardship of organoids:
@natmethods.nature.comDetecting, monitoring and mitigating false positives in lncRNA screens.
@natmethods.nature.comIntroducing bioAFM-DB, a databank for atomic force microscopy data.
@natmethods.nature.comIn a new Points of View, our columnists describe the application of 'principles of proximity' to generate engaging scientific figures.
@natmethods.nature.comIn this month's Editorial, we provide some tips for writing well-structured and professional rebuttal letters for editors and peer reviewers to evaluate.
@natmethods.nature.comOur October issue is live! 🎉
www.nature.com/nmeth/volume...
On the cover, polygenic risk score prediction in diverse populations is made possible with a new computational tool, SPLENDID. Paper: www.nature.com/articles/s41...
@natmethods.nature.comRead the associated Research Briefing, here:
@natmethods.nature.comVIMA: a deep learning-based method to identify differentially enriched features in spatial datasets.
@natmethods.nature.comCCI-seq leverages combinatorial cell clump indexing and single-cell sequencing to capture large-scale cell-cell interaction networks.
@natmethods.nature.comTransferable retention time prediction across liquid chromatographic conditions and compound classes.
@natmethods.nature.comCytoVI: a deep generative model for statistically rigorous analysis of antibody-based single cell data.
@natmethods.nature.comCheck out the @natureportfolio.nature.com Collection of articles related to this year's Nobel Prize in Physiology or Medicine, here:
@natmethods.nature.comBack in 2010 when we selected optogenetics as our Method of the Year, we had already observed the transformative impact that it was making on basic research in neuroscience. www.nature.com/nmeth/volume...
www.nature.com/articles/nme...
It's exciting to see how far the technology has come!
@natmethods.nature.comSpatial Hi-C allows the study of chromatin in a spatially resolved manner, as applied to adult and developing mouse brains.
@natmethods.nature.comGraphene reservoirs formed over perforated support films precisely control ice thickness during cryo-EM sample preparation.
@natmethods.nature.comResolVI: error and batch correction for spatial transcriptomics data.
@natmethods.nature.comSVPG: accurate pangenome-facilitated structural variant detection from long-read sequencing data.
@natmethods.nature.comNanoTS: deep learning-based tool for nanopore long-read transcriptome sequencing-based SNP detection and genotype calling.
@natmethods.nature.comConfinement force microscopy enables tunable cell confinement for measuring traction forces exerted by single cells and cell aggregates.