5/5
We don’t yet know the mechanism. But the lesson is simple: a fluorescent reporter calibrated in one physiological condition cannot automatically be assumed quantitative in another.
Preprint:
www.biorxiv.org/content/10.6...

@paulbrainey.bsky.social
Evolutionary geneticist working with microbes. Absorbed by the curiosity of science and ideas. Department of Microbial Population Biology, MPI for Evolutionary Biology, Plön, Germany & ESPCI, Paris, France.
5/5
We don’t yet know the mechanism. But the lesson is simple: a fluorescent reporter calibrated in one physiological condition cannot automatically be assumed quantitative in another.
Preprint:
www.biorxiv.org/content/10.6...
Margarita Salas revolucionó la biología molecular con la ADN polimerasa phi29 que amplifica ADN con gran rapidez y fidelidad. Su descubrimiento impulsó la genética, el diagnóstico médico y la ciencia forense. Pionera en abrir camino a mujeres en la ciencia.
grupos.eez.csic.es/imili/wp-con...
Best Sunday morning ever… all the rest, but on top, Jessica Riskin’s biography of Lamarck www.penguinrandomhouse.com/books/763654... is beyond a delight.
Why is there no Rue de Vaillant in the 5th arrondissement? Or anywhere else in Paris?
How does pressure from below begin? Often quietly, when early-career researchers discover that a calculation they have been making alone is widely shared. New on Academic Renewal: notes from conversations among ECRs.
📨 You've got (𝘍𝘌𝘉𝘚) 𝘓𝘦𝘵𝘵𝘦𝘳𝘴!
📬 Our latest The Scientists' Forum piece proposes an accreditation system to stop predatory publishing — raising standards and restoring public trust in science.
📡#ResearchIntegrity, #ScholarlyPublishing, #Science
📝 @paulbrainey.bsky.social
A beautiful piece of detective work by @honour.bsky.social + colleagues revealing the origins of Ralstonia disease of bananas on Martinique. As so often, ICEs (ICERs!) prove to be extraordinary capacitors for evolutionary change. Evolution for evolution's sake 🤔
Image generated by AI (GPT Sol 5.6)
A further push to do something about the plague of journals that provide minimal editorial oversight, erode standards, distort incentives and threaten public trust in science; while at the same time reaping vast profit from tax-payer-funded research.
😳😶🌫️🧐
Could major evolutionary transitions arise "from within" -- through internal innovation rather than merger? The case for autogenic transitions in individuality is developed here: philsci-archive.pitt.edu/26847/