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Paul Stamets

@paulstamets.bsky.social

3 Following13.4k Followers

Mycologist, Author, Inventor, Teacher, Earthling

Discover my biography here: https://bit.ly/PaulStametsResume

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@paulstamets.bsky.socialOct 14, 2026, 6:55 AM

Read more: www.sciencedaily.com/rel.../2025/...

Earth’s Natural Internet: dn760105.eu.archive.org/0/items/whol...

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@paulstamets.bsky.socialOct 14, 2026, 6:55 AM

... or components capable of retaining information about previous electrical states. Their mushroom-based devices switched between electrical states thousands of times per second, opening possibilities for biodegradable, low-cost computing systems.

The #MycelialNetwork continues to amaze!

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@paulstamets.bsky.socialOct 14, 2026, 6:55 AM

1999, I postulated that #mycelium could function as a biological computer network. 25+ years later, researchers continue to explore just how far that idea can go.

Scientists at The Ohio State University recently demonstrated that shiitake mushrooms can function as organic “ #memristors ” ...

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@paulstamets.bsky.socialSep 29, 2026, 1:05 PM

📣 Findings from a randomized, double-blind clinical trial may support future pandemic preparedness.

A fungal supplement taken w/ #COVID19 vaccination was safe & well tolerated in a randomized clinical trial.

Press: today.ucsd.edu/story/study-...

Journal article: link.springer.com/article/10.1...

@paulstamets.bsky.socialSep 25, 2026, 8:35 AM

These 2 works challenge the idea that fungal biology can be reduced to 1 biomarker or isolated compound & underscore the need for a systems-level understanding of mycelium to unlock its functional potential. Proud of our R&D Team & grateful to everyone advancing our understanding of these #fungi
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@paulstamets.bsky.socialSep 25, 2026, 8:35 AM

This builds on our recent “Calm Under Challenge” study of lion’s mane mycelium, where we found that #mycelium can help keep the #ImmuneSystem cool under stress, while highly concentrated β-glucan fruiting body extracts produced a divergent response associated w/ overstimulation & imbalance.

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@paulstamets.bsky.socialSep 25, 2026, 8:35 AM

2️⃣ Accepted by Frontiers in Immunology, demonstrates context-dependent immune modulation by agarikon in human imm. cells. It explores potential mechanisms underlying agarikon’s centuries-long ass. w/ vitality & longevity, incl. key oxidative #StressDefensePathways
www.biorxiv.org/content/10.6...

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@paulstamets.bsky.socialSep 25, 2026, 8:35 AM

1️⃣ Accepted by G3, the 1st annotated genome of #agarikon, revealing 27+ biosynthetic gene clusters ass. w/ diverse classes of bioactive compounds. We're applying this framework across our library of 120+ agarikon isolates, incl. 118 w/ complete #genomesequences

www.biorxiv.org/content/10.6...

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@paulstamets.bsky.socialSep 25, 2026, 8:35 AM

Last month marked a major milestone in our mission to conserve, study & unlock the mycelial potential of #agarikon, one of the world’s most extraordinary fungi.

Our R&D Team had 2 manuscripts accepted on the same day, advancing our understanding of agarikon from genetics to functional biology.

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@paulstamets.bsky.socialSep 23, 2026, 7:54 AM

Got a lot of bemused looks walking through the airport.

“You have magic,” one person said.
Indeed I do!

Even airport security seems happy to see this giant #LibertyCap !

Follow the artist on Instagram to order one for yourself (coming soon). www.instagram.com/m_keyhole/

📹 by Pamela Kryskow

@paulstamets.bsky.socialSep 16, 2026, 9:51 AM

Thank you to the World Ayahuasca Forum for creating this space for dialogue, and to everyone who joined me for my talk. Ending in a standing ovation was a moment I will never forget…

Video courtesy of Ancient Future Labs

Learn more about the World Ayahuasca Forum: www.ayahuasca2026.com

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@paulstamets.bsky.socialSep 16, 2026, 9:51 AM

This gathering was a great example of “two-eyed seeing,” bringing Indigenous and scientific ways of knowing together through mutual respect and collaboration. 2/3

@paulstamets.bsky.socialSep 16, 2026, 9:51 AM

Deeply grateful to have been invited by Elder Nixiwaka to speak at #Ayahuasca Forum, where Indigenous knowledge keepers led the way & gave scientists a seat at the table and a place at the podium.

There was a powerful sense of urgency around protecting #Indigenous knowledge, practices & lands.

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@paulstamets.bsky.socialSep 12, 2026, 7:53 PM

Just two doses before chemotherapy protected sensory nerves and prevented pain hypersensitivity, with effects lasting through repeated #chemotherapy cycles.

The science continues to unfold!

Read more: www.science.org/doi/10.1126/...

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#psilocybin #fungi #cancertreatment #CIPN

@paulstamets.bsky.socialSep 12, 2026, 7:53 PM

The potential of #psilocybin continues to surprise us!

🆕research has found that psilocybin prevented #chemotherapy -induced peripheral neuropathy #CIPN in mouse models, a painful & often irreversible side effect of #cancer treatment for which there is currently no proven preventive strategy.

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@paulstamets.bsky.socialJun 12, 2026, 7:57 PM

More amazing news has emerged from the world of #psilocybin research!

A newly published case report describes an 80 year old woman with advanced #Alzheimer’s disease who reportedly experienced significant cognitive & functional improvements following a single high-dose psilocybin intervention.

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@paulstamets.bsky.socialMay 19, 2026, 6:04 AM

Oyster #mushrooms are among the most reliable spring #fungi, returning year after year on aging trees as they slowly decompose the wood. They are not only beautiful and abundant, but also absolutely delicious.

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@paulstamets.bsky.socialDec 29, 2025, 7:11 AM

📣 New research: Lions Mane #Mycelium out performs Lions Mane Fruitbody.

A new article from Fungi Perfecti and Host Defense compared lion’s mane mycelium and fruiting body extracts, and the #immune responses were notably different.

Link to article: www.supplysidesj.com/immune-healt...

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