@ericchevet.bsky.social Thank you for a great visit and a fantastic and inspiring seminar!!
@drsimoncook.bsky.socialSimon Cook
@drsimoncook.bsky.social
Researching Cell Signalling at @babrahaminst.bsky.social Walker; watching woodpeckers; tree hugger; listening to The Jam. European. Views my own. NToR (Never Tory or Reform). I could go on for hours and I probably will....
@drsimoncook.bsky.social@drsimoncook.bsky.socialAs smart as he was handsome and principled!
@rebeccasolnit.bsky.socialReposted by @drsimoncook.bsky.socialTime for this classic again.
@drsimoncook.bsky.socialAnd they need to make sure they plant them at the right time of year, not like the muppets who plant trees along new roads, 90% of which die
@drsimoncook.bsky.socialI am looking forward to welcoming Prof Eric Chevet @ericchevet.bsky.social to The Babraham Institute today when he presents his seminar 'Targeting Endoplasmic Reticulum Proteostasis in cancer'
@paulbernal.bsky.socialReposted by @drsimoncook.bsky.socialNo, BBC, he has not been arrested over the video of dinghy slashing. He’s been arrested over the dinghy slashing. Words matter.
@jcellsci.bsky.socialReposted by @drsimoncook.bsky.socialAnne Ashford, Simon Cook @drsimoncook.bsky.social @babrahaminst.bsky.social and colleagues use phosphoproteomics to identify novel DYRK1B targets and establish DYRK1B as a regulator of processing body abundance.
journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
@drsimoncook.bsky.socialSo Reform UK Ltd either doesn't care two hoots about racism or is tacitly seeking to support racists
@drsimoncook.bsky.social👇🏼👇🏼👇🏼👇🏼👇🏼Completely wrong
@drsimoncook.bsky.socialYou must get a lot of that!
@drsimoncook.bsky.socialI'm delighted to see this beautiful study out. WNT5A hyperactivation drives the pathological ERK1/2 signalling. #RASopathies and implicaitons for cancer, what's not too like?!
Congratulations to Ian, Yeonjoo and all their collaborators! 👏 👏 👏 👏 👏
P.S. Take the rest of the day off!
@nanagale.bsky.socialReposted by @drsimoncook.bsky.social
@guyshrubsole.bsky.socialReposted by @drsimoncook.bsky.social“The rise of anti-migration neofascism is more threatening than anything I’ve seen in my lifetime.”
Good piece by @pollytoynbee.bsky.social challenging Burnham to confront the rise of the far right in his conference speech next week. Features @hopenothate.org.uk
@drsimoncook.bsky.socialwww.theguardian.com/uk-news/2026...
These domestic terrorists -for that is what they are - are undermining key infrastructure and key service provision including charities such as the RNLI, which is the best of Britain
@ayoub.bsky.socialReposted by @drsimoncook.bsky.socialFriend shared this video of a man unveiling the library he hid when he fled Damascus in 2011. It’s incredible
@guyshrubsole.bsky.socialReposted by @drsimoncook.bsky.socialGreat to see the Wildlife Trusts call to “Make access to major rivers, especially those in urban areas, a statutory right.”
Of course, to actually *get to* those rivers, we’d also need a right of responsible access to land, too… @righttoroam.bsky.social
@drsimoncook.bsky.socialKudos to Jack Prescott for spotting the loss of NEMO in the IKK DKO cells, which started the whole project – a great lesson in embracing the unexpected result! Jack was a great PhD student and friend who died tragically young from a rare cancer during his post-doc and is mourned by us all.
@drsimoncook.bsky.socialThis was a ‘slow burn’ study, started by former PhD student Jack Prescott and completed by Kathy Balmanno who took the story further with help from Ellie Griffiths. Thanks also to our collaborators Nadav Myers and Yosef Shaul at the Weizmann.
@drsimoncook.bsky.socialThese results may be relevant to attempts to disrupt IKK:NEMO interactions as an alternative IKK therapeutic. NEMO binds to >100 proteins, some not linked to NF-kB signalling, so these results may have wider implications for NEMO functions, e.g., aggrephagy (doi: 10.1038/s41467-023-44033-0).