@atranscendedman.bsky.social
Transparent to the transcendent.
Building TrialPilot - https://www.trialpilot.app/
https://fnih.org/patient-engagement/patient-voices-fnih/long-covid-struggle-inspires-urgency/
@atranscendedman.bsky.socialCharité Berlin researchers studied 49 Long COVID patients receiving head and neck lymphatic drainage.
Brain fog, concentration, headaches and fatigue improved, raising questions about the brain’s waste clearance system.
Controlled trials are needed.
@atranscendedman.bsky.socialTechnical University of Munich followed 82 Long COVID patients for 6 months and found persistent dysfunction in tiny retinal blood vessels.
Vessel structure improved, but impaired dilation remained, suggesting lasting problems with vascular regulation.
@atranscendedman.bsky.socialIn mice, removing natural killer (NK) cells before COVID mRNA vaccination reduced early inflammation, vaccine mRNA in lymph nodes by over 5-fold, and CD4 T-cell responses.
Yet long-term antibody responses remained largely intact.
@atranscendedman.bsky.socialResearchers at the Education University of Hong Kong studied 195 children and found that those with Long COVID had significantly poorer Chinese spelling performance.
Parents also reported greater reading difficulties, particularly in older children.
@atranscendedman.bsky.socialUCL researchers analyzed records from 7.4 million children in England and found that post-viral fatigue consultations peaked during both the 2009 flu pandemic and COVID-19 pandemic.
Rates were highest among teenagers and girls.
@atranscendedman.bsky.socialResearchers found that SARS-CoV-2 spike and nucleocapsid proteins directly bind a pancreatic protein, triggering amyloid buildup, inflammation, and insulin-producing cell damage in monkeys.
A potential mechanism for post-COVID diabetes.
@atranscendedman.bsky.socialHHS announced a new NIH clinic opening October 5 to study and care for patients reporting health problems after vaccination.
The initiative also expands adverse event reporting, medical record tracking, and vaccine safety research.
@atranscendedman.bsky.socialTexas A&M researchers studied 8,402 SARS-CoV-2-reactive T cells from 42 patients.
Mild COVID showed stronger T-cell responses, while severe cases showed dysfunction.
Findings could help develop better vaccines.
@atranscendedman.bsky.socialMount Sinai researchers studied 30 Long COVID patients and found magnetic therapy improved memory, processing speed, and emotional well-being.
No device-related adverse events occurred. Larger trials are needed.
@atranscendedman.bsky.socialImperial College London researchers studied 24,095 people and found Long COVID is linked to measurable attention and memory deficits, independent of fatigue alone.
Brain fog may reflect distinct disruptions in cognitive function.
@atranscendedman.bsky.socialResearchers analyzed health claims from 151,318 patients, including 25,229 with Long COVID.
Over 3 years, Long COVID patients averaged $79,777 in healthcare costs, with $21,597 in excess spending compared to patients without Long COVID.
@atranscendedman.bsky.socialResearchers at Mardan Medical Complex report 1 patient with persistently low platelets for 5 years after COVID-19, suggesting the infection may trigger lasting immune dysfunction in which the immune system attacks the body's own platelets.
@atranscendedman.bsky.socialResearchers analyzed over 900 gut biopsies from patients with Crohn’s disease and ulcerative colitis
They found cell death signals in seemingly healthy tissue that predicted relapse over 2-3 years, suggesting inflammation may begin before visible damage
@atranscendedman.bsky.socialTechnical University of Munich researchers studied 102 Long COVID patients and found that weaker muscles and poorer recovery were linked to blood vessel dysfunction.
Higher SARS-CoV-2 spike antibodies were also associated with muscle impairment.
@atranscendedman.bsky.socialA review of 110 studies suggests Long COVID may accelerate biological aging and cardiovascular disease in younger adults.
Persistent viral RNA and immune activation may drive chronic inflammation, vascular damage, and cellular dysfunction.
@atranscendedman.bsky.socialRuhr University Bochum studied 9 Long COVID patients with persistent spike protein.
Monoclonal antibodies significantly reduced β1-adrenergic autoantibodies, but not circulating spike or symptoms.
@atranscendedman.bsky.socialDeakin University researchers studied muscle cells derived from 6 ME/CFS patients and 7 controls, finding altered mitochondrial quality control, calcium signaling and RNA processing, offering new clues to muscle dysfunction and post-exertional malaise.
@atranscendedman.bsky.socialUniversity of Liverpool researchers studied 3 cancer patients and healthy donor samples, finding that blocking PD-1/PD-L1 immune checkpoints strengthened memory T-cell responses to SARS-CoV-2, increasing cell proliferation and antiviral signaling.
@atranscendedman.bsky.socialResearchers in Kenya studied 303 people living with HIV and found that missing antiretroviral doses was linked to higher rates of COVID-19 infection.
The findings raise questions about how HIV treatment and immune health influence SARS-CoV-2 outcomes.
@atranscendedman.bsky.socialStanford researchers, >220 lung donors.
SARS-CoV-2 infected lung epithelium and activated local virus-specific resident T cells.
Boosting them cut viral RNA 36% and infectious virus 45%, showing local lung immunity can restrain infection.