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A Protocol and People card on a pale cream background. The question reads: What is grade, and how is it different from stage? The card turns over to the answer: Stage is about how far it has spread. Grade is about how the cells look under the microscope, and how fast they are likely to grow. Dr Oye, an illustrated doctor in a white coat and teal scrubs with an orange stethoscope, stands beside the card and says: So two people can share a stage and have very different grades. Both are used to choose treatment. Ask us for yours, and ask what each one is telling you.