#ICU Evidence #001-002:

Two septic shock trials. Two different drugs. One missing piece

#Dobutamine improved kidney outcomes
Earlier #vasopressin changed practice, but not mortality

But who actually needed the drug?

Maybe the next trial should start somewhere else:

Presented at #LIVES2026:

Among patients with #SepticShock, a hospital-level strategy recommending #Vasopressin initiation at a lower dose threshold of other vasopressors did not reduce 28-day mortality vs a higher threshold strategy.

ja.ma/4B6K4BU