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@sigtrans-sttt.bsky.socialOct 17, 2026, 12:01 PM

How does SRSF11 #Succinylation drive #Radioresistance in #LiverCancer?

This study shows that KAT2A promotes RAD52 splicing and RAD51-dependent DNA repair, identifying a potential target for radiosensitization.

#STTT #OpenAccess: doi.org/10.1038/s413...
#CancerDiagnosis #AIinMedicine

KAT2A-driven succinylation of SRSF11 enforces spliceosome-mediated RAD52 splicing to promote homologous recombination and radioresistance in hepatocellular carcinoma
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