Researchers have identified the protein PDβL2 as a shield that lets senescent cells dodge the immune system, opening a potential therapeutic route to curb ageβrelated inflammation.
#science #PDL2 #senescence

Researchers have identified the protein PDβL2 as a shield that lets senescent cells dodge the immune system, opening a potential therapeutic route to curb ageβrelated inflammation.
#science #PDL2 #senescence
M'ning Bsky Its Happenibg #Autumn the big colour change #Trees #Woods #Woodland #Parks #Botany #flora #Nature #NaturalHistory Another year of #Mast ? Colour Fruits & Berries Join me to look at some ephemeral concepts #Senescence #MastYear from 2025 as we take a woodland stroll youtu.be/97cTFBk-wC8
Vascular aging is the primary cause of human mortality, leading to atherosclerosis and vessel rupture. The vascular network loses capillary density and smooth muscle function, increasing risks of heart attacks and strokes.
Agingβs Special Collection on Cell Senescence and Rapamycin:
https://www.aging-us.com/special-collections-archive/cell-senescence-and-rapamycin
#aging #senescence #rapamycin #research #science #meded #openaccess #publications
Experimental Anti-Aging Cream Shows Promise in Reducing Skin Biological Age
π€ IA: It's not clickbait β
π₯ Users: It's not clickbait β
#antiaging #skinhealth #senescence
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While the immune system clears senescent cells efficiently in youth, this clearance mechanism falters in later life, allowing these cells to accumulate.
After genotoxic stress: apoptosis clears damaged cells early, while senescent fraction accumulates over time. Simulated, literature-grounded trend.
Senescent cells may have a chemical fingerprint.
RamanOmics pairs Raman imaging with spatial transcriptomics. In old mouse lung & skin, a lipid-linked signal marked p21+ cells. Mouse data, correlation only.
doi.org/10.1038/s435...
doi.org/10.1038/s435...
#Senescence
This work identified epithelial #senescence-associated signaling as a mechanism linking prostate epithelial alterations to fibroblast reprogramming and #ExtracellularMatrix remodeling.
Check out the #OpenAccess paper. π
Researchers identified 287 unique gene variants that keep epigenetic switches regulating DNA repair and metabolism active. This prevents the accumulation of genetic wear and tear typically seen in aging Aldabrachelys gigantea.
π’ #CallforPapers:
Aging invites #submissions on cellular #senescence - its mechanisms, functions & clinical applications - in memory of Dr. Judith Campisi.
π Deadline: October 31, 2026
π Details:
https://www.aging-us.com/judith-campisi-commemorative-call-for-papers
π #PaperSpotlight:
"Spatially fractionated mini-GRID radiotherapy differentially modulates radiation-induced senescence in murine glioma and normal cells"
#PressRelease β¬οΈ
https://bit.ly/470cOyv
#Aging #Radiotherapy #Glioma #Senescence #Cancer #OA #PeerReviewed #Publishing
Check out the MitoBlog Q&A w/ authors of @nature.com paper: #Mitochondrialmetabolism & epigenetic crosstalk drive #SASP. Peter Adams & Joao Passos reveal a new #mitochondria #senescence #inflammaging pathway.
π₯ #AgingShort:
Abstract #Video about the #Research paper, titled "Selective targeting of cancer and senescence via shared metabolic shifts extends lifespan of old mice.β
@qb3-berkeley.bsky.social @ucberkeleyofficial.bsky.social
π #PaperSpotlight:
The #Research paper, titled "Selective targeting of cancer and senescence via shared metabolic shifts extends lifespan of old mice," was #Published in Volume 18.
New review!
Myrthe Klaver et al @demarialab.bsky.social reflect on the field of cellular #senescence and its continuing evolution, from initial discoveries to technology-driven conceptual transitions and the emerging era of targeted interventions
#WeekendRead
link.springer.com/article/10.1...
π #PaperSpotlight:
The #Review, "Developmental senescence misregulation in congenital disorders: CHARGE syndrome as a candidate model," was recently published in Volume 18.
Sophierce shares latest release with new single "Senescence"
#sophierce #senescence #new #music #newmusic #newmusicnow #indie #pop #indiepop #altpop #alternativepop #avantpop #artist #singersongwriter #uk #plastic #plasticmag
π₯ #AgingShort:
Abstract #Video about this #Research paper #Published in Volume 18, titled "TM4SF1 is a surface marker of senescent pancreatic Ξ²-cells.β
π https://doi.org/10.18632/aging.206398
#Aging #TrendingWithImpact #Senescence #Diabetes #OpenAccess #PeerReview #Publishing #MedEd