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@alicefrolov.bsky.socialOct 14, 2026, 5:04 PM

Rapamycin dose-response for S6K1-T389 shifts rightward with age: higher EC50, mTORC1 harder to inhibit. Simulated data, literature-grounded trend.

#MTORC1 #AgingBiology #Rapamycin

Grid of dose-response curves showing S6K1-T389 phosphorylation (y-axis) versus rapamycin dose (x-axis) by age group. Old muscle requires about 4x more rapamycin to halve phosphorylation, with EC50 shifting from 2.1 to 8.6 nM.Grid of dose-response curves showing S6K1-T389 phosphorylation (y-axis) versus rapamycin dose (x-axis) by age group. Old muscle requires about 4x more rapamycin to halve phosphorylation, with EC50 shifting from 2.1 to 8.6 nM.
@aging-us.bsky.socialOct 13, 2026, 2:00 PM

Aging’s Special Collection on Cell Senescence and Rapamycin:

https://www.aging-us.com/special-collections-archive/cell-senescence-and-rapamycin

#aging #senescence #rapamycin #research #science #meded #openaccess #publications

@aging-us.bsky.socialOct 10, 2026, 8:00 PM

🎧 Listen to our #PressRelease on the #Essay, titled "Misha Blagosklonny: a life of ideas."

https://bit.ly/4xurbpR

#MikhailBlagosklonny #Podcast #Audio #SoundCloud #PaperSpotlight #Aging #Lifespan #Longevity #Rapamycin #OA #PeerReviewed #Publishing #Press

@aging-us.bsky.socialOct 10, 2026, 4:00 PM

🔆 #PaperSpotlight:
A new #Essay was recently #Published in Volume 18, titled "Misha Blagosklonny: a life of ideas."

#PressRelease ⬇️
https://bit.ly/4qaj1k0

#MikhailBlagosklonny #Aging #Longevity #Gerontology #Rapamycin #HealthyAging #Press #OA #PeerReviewed #Publishing

@aging-us.bsky.socialOct 10, 2026, 2:00 PM

🔬 Aging Special Collection on Cancer and mTOR:

https://www.aging-us.com/special-collections-archive/cancermtor

#aging #cancer #mTOR #rapamycin #research #science #meded #openaccess #publications #collections

@fds3rd.bsky.socialSep 30, 2026, 6:35 PM

#Rapamycin Boosts Brain Blood Flow in #Alzheimer’s Gene Carriers
#Neurology #Neuroscience

@fds.wsocial.euSep 30, 2026, 6:35 PM

#Rapamycin Boosts Brain Blood Flow in #Alzheimer’s Gene Carriers
#Neurology #Neuroscience

@aging-us.bsky.socialSep 27, 2026, 2:00 PM

⏳ Aging’s Special Collection on Longevity and Rapamycin:

https://www.aging-us.com/special-collections-archive/longevity-and-rapamycin

#aging #longevity #rapamycin #research #science #meded #openaccess #publications #publishing

@aging-us.bsky.socialSep 27, 2026, 12:00 AM

🧬 Longevity & Aging Series (S3, E6):
Girish Harinath from AgelessRx discusses “Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results.”

🎥 https://www.youtube.com/watch?v=7-NvskI8Ve0

#interview #aging #rapamycin #geroscience #longevity #healthspan #series #meded

@aging-us.bsky.socialSep 24, 2026, 2:00 PM

🔬 Aging Special Collection on Cancer and mTOR:

https://www.aging-us.com/special-collections-archive/cancermtor

#aging #cancer #mTOR #rapamycin #research #science #meded #openaccess #publications #collections

@epigenometech.bsky.socialSep 22, 2026, 7:15 AM

Epigenetics Update - Rapamycin targetome mining identifies RBBP7 as a druggable epigenetic vulnerability in hepatocellular carcinoma u.epigenome.us/jje91JhP

Bing Shan & Yaoyang Zhang (CAS) in Cell Chemical Biology

#Epigenetics #RBBP7 #Cancer #Rapamycin
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epigenometech.com

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@aging-us.bsky.socialSep 14, 2026, 10:00 PM

✅ A recent essay published in Aging, “Misha Blagosklonny: a life of ideas,” explores his life, scientific legacy, and groundbreaking ideas on aging, hyperfunction, rapamycin, and longevity.

🔗 Summary:
https://bit.ly/4iu38Dd
#Blagosklonny #Aging #Longevity #Rapamycin #Lifespan

@aging-us.bsky.socialSep 13, 2026, 2:00 PM

⏳ Aging’s Special Collection on Longevity and Rapamycin:

https://www.aging-us.com/special-collections-archive/longevity-and-rapamycin

#aging #longevity #rapamycin #research #science #meded #openaccess #publications #publishing

@aging-us.bsky.socialSep 11, 2026, 2:00 PM

🔬 Aging Special Collection on Cancer and mTOR:

https://www.aging-us.com/special-collections-archive/cancermtor

#aging #cancer #mTOR #rapamycin #research #science #meded #openaccess #publications #collections

@aging-us.bsky.socialSep 11, 2026, 2:00 AM

Aging’s Special Collection on Cell Senescence and Rapamycin:

https://www.aging-us.com/special-collections-archive/cell-senescence-and-rapamycin

#aging #senescence #rapamycin #research #science #meded #openaccess #publications