#Targetome
Retrospective analysis: 20.2% of Chinese older adults filled 2+ CPIC level-A drugs yearly; CYP2C19, SLCO1B1, CYP2C9 dominate coverage.
Details: https://www.maxapress.com/article/doi/10.48130/targetome-0026-0043
#Pharmacogenomics #Polypharmacy #Geriatrics

Do Your Medications Play Well Together?
Many seniors take multiple medications and supplements. They need to know if these medications are safe to take together. www.thedoctorwillseeyounow.com/content/agin... @jama.com #druginteractions #seniors #SeniorHealth #prescription Drugs.com #polypharmacy

🚨ICYMI - our MOST-VIEWED new TI video in 2025:

Addressing medications that are ineffective & potentially harmful for patients with alcohol & other substance use disorders 💊🍻🚬
ti.ubc.ca/harms-aud-sud/

Speaker: Dr. Evan Wood

#alcohol #polypharmacy #BetterPrescribing

🆕In their Article, Steven Gilmore and colleagues investigated the occurrence of #prescribing cascades and their effects on problematic #polypharmacy in a cohort of community-dwelling older adults

Read the full Article here ➡️ www.thelancet.com/journals/lan...
#primarycare #medsky #familymedicine

Polypharmacy initiative in mental health strategy ‘paused’

https://bit.ly/4dg6ZQM

@TCDPsychiatry @IrishPsychiatry @MHReform @HSELive @roinnslainte #mentalhealth #polypharmacy

Polypharmacy initiative in mental health strategy ‘paused’

https://bit.ly/4dg6ZQM

@TCDPsychiatry @IrishPsychiatry @MHReform @HSELive @roinnslainte #mentalhealth #polypharmacy

Tapering off one medication can trigger a cascade of prescriptions — replacing withdrawal symptoms with new drugs until you’re taking six just to cope. We must address polypharmacy, safer deprescribing, and patient-centered care. #Polypharmacy #Deprescribing #MedicationSafety #PatientSafety http

Polypharmacy initiative in mental health strategy ‘paused’

https://bit.ly/4dg6ZQM

@TCDPsychiatry @IrishPsychiatry @MHReform @HSELive @roinnslainte #mentalhealth #polypharmacy

Polypharmacy initiative in mental health strategy ‘paused’

https://bit.ly/4dg6ZQM

@TCDPsychiatry @IrishPsychiatry @MHReform @HSELive @roinnslainte #mentalhealth #polypharmacy

🚨ICYMI - our MOST-VIEWED new TI video in 2025:

Addressing medications that are ineffective & potentially harmful for patients with alcohol & other substance use disorders 💊🍻🚬
ti.ubc.ca/harms-aud-sud/

Speaker: Dr. Evan Wood

#alcohol #polypharmacy #BetterPrescribing

Polypharmacy initiative in mental health strategy ‘paused’

https://bit.ly/4dg6ZQM

@TCDPsychiatry @IrishPsychiatry @MHReform @HSELive @roinnslainte #mentalhealth #polypharmacy

A population-level retrospective cohort study found that common #medications can trigger #PrescribingCascades in #OlderAdults, leading to additional #drugs for #SideEffects and increasing medication-related #harm and healthcare costs. 
#Polypharmacy

🚨ICYMI: UBC TI #BestEvidence webinar recording

Safe & sound: #Polypharmacy & rational primary care
ti.ubc.ca/drugevidence24

Dr. Dee Mangin describes key aspects of primary care in maximizing therapeutic benefit + provides examples/areas of challenge for rational tx

[2/2] Two similar patients (on paper) could be on identical meds. After a medication review, one may choose to continue everything and the other may wish to stop one or more medicines. And both outcomes could represent good care. We need to be careful what we measure when we talk about #polypharmacy

It's great that @shaunlintern.bsky.social has more stories to follow on this. As mentioned by others, there's lots of research going on about how to tackle #polypharmacy but one of the key challenges is what you define as a successful intervention. [1/2]

Almost 8 million over 50s are taking 5 medicines a day - the threshold for #polypharmacy - About 2.2 million take 10 drugs a day. For frail, elderly patients drugs can have cumulative, harmful effects and the NHS just isn't geared up to tackle the problem:
#tomorrowspaperstoday