@dnanexus.bsky.socialOur team demonstrates how we worked with Ovation to examine GLP-1 treatment response from an EHR-linked whole-genome cohort of several thousand patients.
Register: hubs.ly/Q04zNzjR0
#GLP1 #Pharmacogenomics #MachineLearning #Genomics #DNAnexus
@transpread.bsky.socialA study published in Targetome identifies frequent annual exposure to genetically relevant medications and a small core gene set that warrants further evaluation for targeted pharmacogenomic testing.
#Geriatric #Pharmacogenomics
Details: doi.org/10.48130/tar...
@tenuretracker.bsky.socialUniversity of California, Davis (@ucdavis.bsky.social) is hiring:
Academic Research Scientist in Pharmacogenomics
@gmj-georgia.bsky.socialYour 2pm coffee cutoff might be wrong—for you. A single gene variant determines whether you clear caffeine in 4 hours or 7+ hours. Half the population should stop drinking coffee by … #Caffeine #CYP1A2 #Genetics #Pharmacogenomics #Sleep #Caffeine #CYP1A2 #Genetics #Pharmacogenomics #Sleep http…
@mapjournals.bsky.social#Targetome
Retrospective analysis: 20.2% of Chinese older adults filled 2+ CPIC level-A drugs yearly; CYP2C19, SLCO1B1, CYP2C9 dominate coverage.
Details: https://www.maxapress.com/article/doi/10.48130/targetome-0026-0043
#Pharmacogenomics #Polypharmacy #Geriatrics
@genox-veille.frClopidogrel is first-line for secondary stroke prevention, but its effectiveness depends on CYP2C19 genotype.
SAME MEDICINE DIFFERENT REACTION
Why can the same medicine affect people differently? An NHS-funded pilot found 9/10 had a gene result relevant to prescribing—but only 1/4 had a medicine changed. Testing may guide some choices, but it isn’t routine for everyone. Would you want it? #Pharmacogenomics
@gmj-georgia.bsky.socialCaffeine doesn't create energy—it blocks the fatigue signal. Your tiredness keeps accumulating; you just can't feel it. And whether this matters depends on y… #Caffeine #Cardiovascularhealth #CYP1A2 #Personalizedmedicine #Pharmacogenomics #Caffeine #Cardiovascularhealth #CYP1A2 #Personalizedmed…
@dnanexus.bsky.socialOur upcoming webinar is a case study on therapeutic response examining glycemic response, side effects, and the influence of germline variants on these with our partners Ovation. Register: event.on24.com/wcc/r/549955...
#GLP1 #Pharmacogenomics #PrecisionMedicine #Genomics #DNAnexus
Pharmacogenomics asks whether genetic differences could help explain why a medicine works for one person but not another. It can inform choice or dose for some medicines—not all—and never replaces the full clinical picture. Would you choose DNA or NOT YET? #Pharmacogenomics
@pharmaj.bsky.socialIn this blog article, #AdrushaRamsunder and #RachelPalmer explore what progress has been made towards a genomics population health service, what challenges need to be overcome and what is the role of pharmacy?
@hsr-scicomm.bsky.socialHolistic oncology care requires looking closely at drug-drug interactions. This latest blog from Rorisang Moletsane highlights how certain antidepressants can dampen Tamoxifen efficacy in ER+ breast cancer patients. 🔬📚
@elozz.bsky.socialToday at the FISV symposium on pharmacogenetics 👀🧬
@genox-veille.frCurrent DPYD genotyping panels explain only a limited share of severe fluoropyrimidine toxicity.
@fiosgenomics.bsky.socialThe goal of #pharmacogenomics is to improve patient outcomes by tailoring drug therapies to an individual’s genetic makeup🧬💊. #Bioinformatics supports this vital research in various ways, find out more at https://www.fiosgenomics.com/pharmacogenomics-and-bioinformatics/
#personalisedmedicine
@genox-veille.frTwo population-based cohorts were analysed in parallel: GoDARTS, with 41 802 patients initiating one of six major glucose-lowering drug classes, of whom 11 615 had genotype data, and UK Biobank, with 9 371 individuals including 8 293 with genetic data.
@genox-veille.frMatched case-control study conducted at two US academic medical centres (Vanderbilt and Mass General Brigham), including 29 patients with RegiSCAR-confirmed lamotrigine-induced DRESS (score ≥ 4) and 290 lamotrigine-tolerant controls matched on sex, self-reported ra…
@junjyang.bsky.socialDay 1 for @zhengwu1.bsky.social at @stjuderesearch.bsky.social! Very excited to welcome him as the newest faculty member in our Division of Pharmaceutical Sciences. Looking forward to the science and collaborations ahead! #StJude #PharmaceuticalSciences #NewFaculty #CancerResearch #Pharmacogenomics
@codon-comms.bsky.social📣Yourgene Health (Novacyt Group) announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene Insight DPYD assay.
#pressrelease 🗞️ yourgenehealth.com/company/8-se...
#PGX #DPYD #pharmacogenomics #DPD #chemotoxicity #IVDR #patientsafety #messengersinscience
@jamapsychiatry.com💡 Special Communication: In psychiatry, #PolygenicScores, rare variant testing, and #Pharmacogenomics may have value when used selectively to inform diagnosis, prognosis, monitoring, and medication safety rather than population-wide screening.
