How does the #nucleolus shape early development?
This review explores its remodeling in oocytes and embryos, highlighting roles in chromatin organization, #epigenetic inheritance, oocyte maturation and #EmbryonicDevelopment.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...

Nucleolar dynamics are determined by the ordered assembly of the #ribosome. New study from Jessica Sheu-Gruttadauria and collegues (UCSF):
rupress.org/jcb/article/...

#Biophysics #RNAbiology #Nucleolus

In @jcb.org, Jessica Sheu-Gruttadauria et al. show that the material properties of the #nucleolus are shaped by the assembly state of ribosomal precursors, which tune nucleolar dynamics and morphology through their interactions with the nucleolar scaffolding protein NPM1. rupress.org/jcb/article/...

Jessica Sheu-Gruttadauria et al. show that the material properties of the #nucleolus are shaped by the assembly state of ribosomal precursors, which tune nucleolar dynamics and morphology through their interactions with the nucleolar scaffolding protein NPM1. rupress.org/jcb/article/...

#Biophysics