T-cell engagers in solid tumors and #neurotoxicity?
Have a look to this new systematic #review in #TAMO: 36 studies, 2.743 patients. ICANS occurred in 6.3%, mainly with #DLL3-targeting agents; severe events were uncommon.
buff.ly/HF05H6u
@MarianaBrandao0 @sandrineaspesla

Depression can amplify Gelsemium elegans neurotoxicity.

CJNM links this effect to disruption of the Clostridium-LCA-PXR-CYP3A11 detox axis.

doi.org/10.1016/S187...
#Depression #Microbiome #Neurotoxicity #CJNM

Element Scientific Exploration Seminar

Prof. Jack Rogers (Harvard Medical School) on lead and manganese neurotoxicity. 📅 Oct 10 | 08:30 UTC+8

🔗 Register free: oaemesas.feishu.cn/share/base/f... #Neurotoxicity

#Neuroscience #Lead #Manganese #MetalBiology

@fudiwang.bsky.social

Up next: Dr. Caleb McEntire on "Neurotoxicity of Cancer Immunotherapy." When these patients deteriorate, neurohospitalists are often the first call. Neurohospitalist

#Neurotoxicity #NHS2026

Cisplatin causes neuronal death by activating nucleotide excision repair (NER), which paradoxically promotes damage instead of protecting neurons. #Neurotoxicity PMID:42269607, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00584-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪