🔬 From our October issue (rupress.org/jem/issue/22...):
Yang Yu et al. (doi.org/10.1084/jem....) demonstrate that CAMKV kinase drives #neuroblastoma growth and acts as a novel therapeutic target. Image shows endogenous CAMKV and CREB interaction in SK-N-AS cells by in situ proximity ligation assay.

Preclinical study finds that blocking a protein makes #neuroblastoma cells easier for the #ImmuneSystem to detect and more vulnerable to #immunotherapy.
#ImmuneResponse #ImmunotherapyResponse

Research: doi.org/10.1177/2542... Journal of Alzheimer's Disease Reports, Sage Journals @journals.sagepub.com

#Curcumin #Neuroblastoma #CancerResearch #BiomedicalResearch #TheScienceMatters

CAMKV kinase drives #neuroblastoma growth and acts as a novel therapeutic target. New study from Yang Yu, Yanling Zhao, Zhongcheng Shi, Larry L. Wang, Chunchao Zhang, Jianhua Yang @childrensnational.bsky.social and colleagues:
rupress.org/jem/article/...

#SolidTumors

In @jem.org, Yang Yu, Yanling Zhao, Zhongcheng Shi, Larry L. Wang et al. demonstrate that CAMKV, previously classified as a nonfunctional pseudokinase, possesses intrinsic kinase activity driven by MYC/MYCN oncogenes to promote #neuroblastoma growth. rupress.org/jem/article/...

Yang Yu, Yanling Zhao, Zhongcheng Shi, Larry L. Wang, Chunchao Zhang, Jianhua Yang et al. demonstrate that CAMKV, previously classified as a nonfunctional pseudokinase, possesses intrinsic kinase activity driven by MYC/MYCN oncogenes to promote #neuroblastoma growth. rupress.org/jem/article/...

On this #ChildhoodCancerAwarenessMonth, we honor children and families affected by cancer and recognize the UChicago Cancer researcher's role in turning shared data into discoveries that advance pediatric cancer care. @UChicagoMed @ComerChildrens #DataCommons #Neuroblastoma
https://ow.ly/bnER50ZJBWk