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@sigtrans-sttt.bsky.socialOct 5, 2026, 3:45 PM

Loss of βPIX in alveolar type 2 cells impairs stemness through reduced Wnt/β-catenin signaling, promoting transitional senescent progenitors and #Myofibroblast activation that drive spontaneous #PulmonaryFibrosis.

#STTT #OpenAccess: doi.org/10.1038/s413...
#CancerAntigens

Alveolar epithelial depletion of βPAK-interacting exchange factor drives spontaneous pulmonary fibrosis by impairing stemness
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