How can #Bioengineering improve #mRNAvaccine #Immunogenicity?
This review explores how RNA architecture and delivery platforms coordinate antigen expression, innate immune activation, and adaptive immune responses.
@sigtrans-sttt.bsky.social
@sigtrans-sttt.bsky.socialHow can #Bioengineering improve #mRNAvaccine #Immunogenicity?
This review explores how RNA architecture and delivery platforms coordinate antigen expression, innate immune activation, and adaptive immune responses.
@coupdegraz7.bsky.social
@gmj-georgia.bsky.social🔬 mRNA cancer vaccines use an unexpected immune backup system that scientists didn't know about until now. This discovery could lead to… #Cancerimmunotherapy #Immunemechanism #MRNAvaccine #Precisiononcology #Vaccinedevelopment #Cancerimmunotherapy #Immunemechanism #MRNAvaccine #Precisiononcolog…
@thelolgic.bsky.socialMerck and Moderna's mRNA vaccine became the first neoantigen cancer therapy to clear Phase 3 trials, outperforming Keytruda alone at preventing melanoma's return in 1,000+ patients.
FDA approval is next step.
@oddlytruejp.bsky.socialđź’‰ Why do some vaccines last decades and others fade in months?
A Japanese team found the antibody's class decides it.
Share of long-lived plasma cells in marrow:
flu 7.3%
tetanus 2.1%
mRNA spike 0.14% — found in only 6 of 17 people
