Among patients with #AtrialFibrillation, catheter-based #LeftAtrialAppendageClosure had similar overall stroke and major bleeding rates vs oral anticoagulation, but higher ischemic stroke risk and lower nonprocedural major bleeding. ja.ma/4hWSnHA

💬 Viewpoint: The role of #LeftAtrialAppendageClosure in #AtrialFibrillation may depend on patient phenotype, and more evidence is needed in patients who cannot take long-term direct oral anticoagulants. ja.ma/3TUWgVv