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@elenasgarbossamd.bsky.socialOct 11, 2026, 12:21 PM

Dear colleagues,

Always remind patients that we humans have zero need to eat cholesterol. We synthesize it. We’re healthier when we eat exclusively plants & mushrooms πŸŒ±πŸ„

… and may never need to worry about our #LDL-c levels 😎

#ApoB #HeartDisease #cardiology #MedSky #Cholesterol #diet #ItsTheDiet

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@thelancetendo.bsky.socialOct 11, 2026, 10:21 AM

Read more about the evolution of novel pharmacological approaches for lipid lowering during the first quarter of the 21st century
thelancet.com/journals/lan...
#LDL #cholesterol #cardiovascular #disease #prevention

#MedSky #EndoSky #CardioSky

A transition from daily oral small molecules to long-acting biologic and nucleic acid-based therapies, including monoclonal antibodies, RNA-targeted agents, immunisation strategies, and gene-editing technologies, delivered subcutaneously or intravenously at extended intervals. Despite this temporal representation, new small molecules and other oral therapies continue to be actively developed, reflecting ongoing innovation across both oral and long-acting treatment platforms.
@thelancetendo.bsky.socialOct 11, 2026, 10:21 AM

#Cholesterol-lowering medicine has changed almost beyond recognition over the past 25 yearsβ€”from early #statin trials to today's longer-acting, less frequently dosed therapies, some of which may eventually require only one or two doses a year youtube.com/watch?v=atCH...
#LDL #CVD
#MedSky #CardioSky

@thelancetendo.bsky.socialOct 11, 2026, 9:25 AM

#Familial #hypercholesterolaemia is an autosomal, semi-dominant condition characterised by markedly elevated plasma #LDL #cholesterol concentration from birth, xanthomas, & early onset of #atherosclerotic #cardiovascular disease (#ASCVD) thelancet.com/journals/lan...
#HeFH #HoFH

#EndoSky #CardioSky

Previous manifestations of ASCVD, especially myocardial infarction and an elevated coronary plaque burden on cardiac CT, indicate a higher risk for ASCVD events. The risk depends not only on very high LDL cholesterol concentrations or exposure to elevated LDL cholesterol during lifetime, but also on the presence or risk biomarkers like male sex, high lipoprotein(a), low HDL cholesterol, high BMI and blood pressure, family history of early ASCVD, smoking and comorbidities like diabetes and chronic kidney disease. Specific familial hypercholesterolaemia risk equations, such as SAFEHEART-RE and the familial hypercholesterolaemia risk score, can integrate this risk. ASCVD risk might also be modulated by the effect of genes unrelated to lipids, as aggregated in a polygenic risk score. LDL cholesterol should always be reduced in patients with familial hypercholesterolaemia. Severe familial hypercholesterolaemia is a clear indication for more intensive LDL cholesterol lowering with PCSK9 inhibitors. ASCVD=atherosclerotic cardiovascular disease.
@neurologyadvisor.bsky.socialOct 7, 2026, 8:31 PM

Among patients with a history of ischemic stroke, achieving a relative #LDL cholesterol decrease of 50% or more was associated with a lower risk for recurrent #stroke, myocardial infarction, and all-cause mortality.

https://www.neurologyadvisor.com/news/ldl-cholesterol-reduction-risk-poststroke/

@thelancetendo.bsky.socialOct 7, 2026, 10:52 AM

Also check out the linked Video Abstract:

25 Years of Lipid Medicine www.youtube.com/watch?v=atCH...
#LDL #cholesterol

@thelancetendo.bsky.socialOct 7, 2026, 10:52 AM

Major transformations in #lipid #metabolism & #cardiovascular disease prevention have occurred during the first quarter of the 21st century & have impacted clinical practice. Find out more in this TimeCapsule article www.thelancet.com/journals/lan...
#LDL #cholesterol

#MedSky #EndoSky #CardioSky

@snacknutrition.bsky.socialOct 5, 2026, 9:24 PM

"Oxidized PUFAs inside low-density lipoproteins (LDLs) trigger immune responses, prompt macrophage uptake, and promote arterial #plaque buildup."
#health #nutrition #diet #pufa #ldl #cvd

Oxidized PUFAs
@snacknutrition.bsky.socialOct 5, 2026, 9:20 PM

Interesting Article - Cholesterol Feeding
"Egg supplementation raised high density and low density lipoprotein #cholesterol levels by 18 and 40%, respectively."
#health #nutrition #diet #healthydiet #eggs #egg #ldl #cvd

Egg supplementation raised high density and low density lipoprotein cholesterol levels by 18 and 40%, respectively.
@thelancetendo.bsky.socialSep 29, 2026, 9:45 AM

Also read the original TimeCapsule article:
A quarter-century of progress: innovations in lipid medicine that transformed cardiovascular prevention thelancet.com/journals/lan...
#LDL #cholesterol #ASCVD #statins #PCSK9 inhibitors

#MedSky #EndoSky #CardioSky

@thelancetendo.bsky.socialSep 29, 2026, 9:45 AM

25 Years of Lipid Medicine youtube.com/watch?v=atCH...
#LDL #cholesterol #ASCVD
#statins #PCSK9 inhibitors

#MedSky #EndoSky #CardioSky

@heinzvhoenen.bsky.socialSep 28, 2026, 9:09 AM

New Treatment Cuts β€œBad” Cholesterol in Half for a Full Year

cc @nanoappsmedical.bsky.social @cellrep7.bsky.social @amandascott2023.bsky.social
#NanoApps #Research #SDGs #GHCE #Cholesterol #HDL #LDL
www.nanoappsmedical.com/new-treatmen...

@elenasgarbossamd.bsky.socialSep 26, 2026, 11:56 AM

Dear colleagues,

Let’s share with everyone what we now know about nutrition: best diet for health, and possibly longevity? ‡️

A whole foods plant-based diet πŸ…πŸ«‘πŸ₯—πŸ„β€πŸŸ«πŸ₯‘πŸ πŸ₯•πŸ†πŸ«›πŸ₯”πŸ₯¬πŸ«œπŸ₯’πŸπŸ“πŸ«πŸ₯πŸ‘πŸŽ

Veganism is for everyone πŸ’ͺ🏻😎

#health #diet #ItsTheDiet #cholesterol #LDL #cardiology #nutrition #WFPB #vegan #MedSky

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@newsen.bsky.socialSep 23, 2026, 6:27 PM

Partnership to Improve Cardiovascular Health Grows to Over 500 Advocates Urging CMS Action #Washington #US #Cardiovascular_Health #CMS #LDL-C

@thelancetendo.bsky.socialSep 23, 2026, 8:35 AM

#Cholesterol-lowering medicine has changed almost beyond recognition over the past 25 years β€” from early #statin trials to today's longer-acting, less frequently dosed therapies, some of which may eventually require only one or two doses a year www.youtube.com/watch?v=atCH...
#LDL #ASCVD

#EndoSky

@mentorminute.bsky.socialSep 22, 2026, 1:21 AM

The best breakfast ever!
youtube.com/shorts/7QtE7...

#breakfast #oatmeal #blueberries #almonds #ldl

@thelancetendo.bsky.socialSep 20, 2026, 3:12 PM

Also check out the Video Abstract:
25 Years of Lipid Medicine youtube.com/watch?v=atCH...
#LDL #cholesterol #ASCVD

#MedSky #EndoSky #CardioSky

@thelancetendo.bsky.socialSep 19, 2026, 12:42 PM

This TimeCapsule reviews the major transformations in #lipid #metabolism & #cardiovascular #disease #prevention during the first quarter of the 21st century & their impact on clinical practice thelancet.com/journals/lan...
#LDL #cholesterol #ASCVD
#FREE to read w/reg (also FREE)

#EndoSky #cardioSky

@anonturk.bsky.socialSep 19, 2026, 5:50 AM

πŸ‡ΉπŸ‡· Damar sağlığı iΓ§in LDL hedefi: Daha erken yaşta daha düşük seviye

#TΓΌrkiye #Haber #GΓΌndem #Damar #LDL #Diken #Siyaset

@thelancetendo.bsky.socialSep 17, 2026, 7:46 PM

25 Years of #Lipid Medicine
youtube.com/watch?v=atCH...

#LDL #cholesterol #ASCVD #statins #PCSK9 inhibitors #ezetimibe #RNA-based drugs #gene editing

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