A study published in Targetome on 11 August 2026 reports that CLP290 improved locomotion and induced coordinated neural and metabolic adaptations without restoring dystrophin expression.
#MDX mice #KCC2
Details: doi.org/10.48130/tar...

#Targetome
CLP290-mediated KCC2 activation restores gait, inhibitory neurotransmission, and metabolic balance across the neuromuscular axis in dystrophic mice.
Details: https://www.maxapress.com/article/doi/10.48130/targetome-0026-0041
#Duchenne #KCC2 #Neuromuscular #Metabolomics