Researchers reveal how glycerol-derived lactate drives H4K5 histone #Lactylation and a FOXP3–GK feedback loop in regulatory T cells, enhancing #Immunosuppression in #ColorectalCancer liver metastases.
@sigtrans-sttt.bsky.social
@sigtrans-sttt.bsky.socialResearchers reveal how glycerol-derived lactate drives H4K5 histone #Lactylation and a FOXP3–GK feedback loop in regulatory T cells, enhancing #Immunosuppression in #ColorectalCancer liver metastases.
@gmj-georgia.bsky.socialThe NHS is expanding RSV vaccine access from September 2026: all adults aged 65–74 with chronic respiratory disease or immunosuppressi… #Chronicrespiratorydisease #Immunosuppression #NHSvaccination #Olderadults #Preventivemedicine #Chronicrespiratorydisease #Immunosuppression #NHSvaccination #O…
@zdruzenjeilos.bsky.social💊 Immunosuppressive drugs play a key role in modern nephrology. As highlighted by Dr. Mlinšek, these medications help prevent organ rejection after transplantation and treat diseases in which the immune system attacks the body's own tissues.
#KidneyHealth #Transplantation #Immunosuppression
@amjtransplant.bsky.socialRead "De novo belatacept-based immunosuppression is not associated with increased risk of invasive fungal infection in kidney transplant recipients," by Eichenberger et al in our Sept. issue!
buff.ly/6mY4mAg
#KidneyTransplant #Belatacept #Immunosuppression #FungalInfections
@amjtransplant.bsky.socialIn our Sept. issue: "Impact on survival of T cell–depleting or interleukin-2 receptor antagonist induction therapy in simultaneous heart-kidney transplantation: A national registry analysis," by Tadokoro et al
buff.ly/WJ6BTvx
#HeartKidneyTransplant #InductionTherapy #Immunosuppression
@currentmedscience.bsky.social#PMEPA1 impairs Treg‑mediated #immunosuppression by hyperactivating PI3K/AKT, fueling ESC invasiveness in #Endometriosis. Targeting this axis may restore immune balance and curb progression. #medsky
Read more: doi.org/10.1007/s115...
