#ImmunologyNews The study analysed approximately 12.4 million immune cells from 2,609 adults aged 20 to over 90 years, alongside long-term health data from the UK Biobank...#research #immunology

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#ImmunologyNews The small intestine does more than absorb nutrients, it is also a frontline barrier against pathogens, coordinating complex interactions between epithelial cells and the immune system...#immunology #research

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#ImmunologyNews The nervous and immune systems were once viewed as separate defence systems...#immunology #research #nervoussystem

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#ImmunologyNews During early pregnancy, some maternal neutrophils appear to take on a very different role: supporting placental development...#pregnancy #immunology

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#ImmunologyNews CD1a is highly expressed on Langerhans cells, where it presents lipid antigens to T cells...#research #immunology

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#ImmunologyNews Inborn Errors of Immunity (IEI), genetic conditions that disrupt immune function, can increase susceptibility to cancer...#immunology #research

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#ImmunologyNews There is currently no licensed vaccine specifically targeting Plasmodium vivax partly because we still know relatively little about the antibody targets that provide effective protection...#malaria #immunology

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#ImmunologyNews AI-based protein design is rapidly expanding the toolkit for cancer immunotherapy, but designing a protein that binds its target is only the beginning...#AI #research #immunology

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#ImmunologyNews Immune checkpoint inhibitors (ICIs) have transformed cancer treatment by releasing the brakes on anti-tumour T cells...#cancer #immunotherapy #immunology

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#ImmunologyNews Mutations in TP53 are among the most common changes in cancer...#cancer #immunotherapy #immunology #research

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#ImmunologyNews When a related virus is encountered years later, these pre-existing clones can influence, or even dominate, the new antibody response...#research #immunology

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#ImmunologyNews Around one-quarter of the world's population is estimated to have been infected with Mycobacterium tuberculosis, yet only a minority of infected people develop active TB...#TB #immunology

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#ImmunologyNews Type 1 diabetes is fundamentally an autoimmune disease: the immune system mistakenly targets the insulin-producing β cells of the pancreas...#diabetes #type1 #immunology

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#ImmunologyNews Maternal immune activation during pregnancy has been associated with an increased risk of neurodevelopmental conditions in offspring...#brain #immunology #research

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#ImmunologyNews UV radiation can introduce a substantial number of mutations into melanocytes, the pigment-producing cells of the skin...#melanin #immunology #cancer

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#ImmunologyNews Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is driven by complex interactions between the immune system, intestinal microbes and the gut environment...#IBD #immunology

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