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Version devBuilt at: 2026-10-19 04:14:37 EDT

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@jamaoncology.comSep 17, 2026, 4:00 PM

Meta-analysis: In #HeadAndNeckCancer with programmed cell death 1 ligand 1 combined positive score <1, #ImmuneCheckpointInhibitors were likely associated with reduced survival, including significantly reduced overall survival in recurrent or metastatic disease. ja.ma/46uMnAC

Figure 2: Meta-analyses of ICIs in head and neck squamous cell carcinoma (PD-L1 CPS < 1) by disease setting. A) Recurrent/metastatic: Forest plot shows pooled HRs (Bayesian 1.42, Frequentist 1.46) favor control (P<.001). B) Locally advanced: Pooled HRs (Bayesian 1.19, Frequentist 1.18) also favor control but are not significant (P=.41).
@jamanetworkopen.comSep 8, 2026, 4:15 PM

đź“Š Meta-analysis: In curative treatment of solid tumors, #ImmuneCheckpointInhibitors were associated with improved survival outcomes, with no statistically significant differences by patient sex, however female patients were underrepresented across trials. ja.ma/46ES27c