@sigtrans-sttt.bsky.socialCan dual cytokine blockade address treatment-resistant #HidradenitisSuppurativa?
This study identifies an IL-17/IL-36γ inflammatory hub and demonstrates promising clinical responses and tunnel regression with the #BispecificAntibody HB0043.
@thejidjournal.bsky.socialSee Montgomery et al's Letter:
Distinct IL-17A and retinoic acid–associated gene programs are enriched in epithelialized tunnels in severe #hidradenitissuppurativa
https://doi.org/10.1016/j.jid.2026.09.847
#DermatologyJournal #Dermatology #derm #dermatologist #dermresearch #dermscience
@dhsc-answers.bsky.socialA question on #HidradenitisSuppurativa tabled by Jim Shannon on 10-09-2026 has been answered by Mr James Frith. https://questions-statements.parliament.uk/written-questions/detail/2026-09-10/28730
@thejidinnovations.bsky.socialThe Expression of Interleukin-1β and NLRP3 Inflammasome Components in #HidradenitisSuppurativa Lesional #Skin
Shrotri et al
https://doi.org/10.1016/j.xjidi.2026.100532
#DermatologyJournal #Dermatology #derm #dermatologist #dermatologists #dermresearch #dermscience #dermatologyresearch
@jamadermatology.comIn patients with #HidradenitisSuppurativa, #Interleukin17 inhibitors were not associated with a significant increase in inflammatory bowel disease risk vs placebo, and events were rare.
@dermimmuno.bsky.socialAn experimental set of conversation cards for #HidradenitisSuppurativa was found to be a useful tool to guide HS consultations, though further studies are needed to confirm the impact. #Dermatology