Widespread germline genetic testing has led to a marked increase in the detection of variants of uncertain significance in BRCA1 and BRCA2.
@genox-veille.fr
@genox-veille.frWidespread germline genetic testing has led to a marked increase in the detection of variants of uncertain significance in BRCA1 and BRCA2.
@genomebc.bsky.social🎗️ Breast Cancer Awareness Day is a reminder of the importance of early detection, research and understanding our individual risk.
🧬 Learn how Genome BC is supporting research in this area: https://ow.ly/OwyF50ZW73x
#BreastCancerAwareness #HereditaryCancer #Genomics #PersonalizedMedicine
@genox-veille.frSDH gene variant types differentially influence the risk of thoracic-abdominal paraganglioma-pheochromocytoma (PPGL) and head and neck paraganglioma (HNPGL), but quantitative correlations were lacking.
@jaxeducation.bsky.social🥼🧬 Heading to #JADPROLive?
Join members of @jax.org Clinical Education and the Maine Cancer Genomics Initiative for an interactive session on using biomarkers to guide germline testing decisions.
Learn practical approaches to using biomarkers in #HereditaryCancer risk assessment. See you there! 👇
@genox-veille.frFew at-risk relatives complete cascade genetic testing despite its potential public health impact.
@lmg622.bsky.socialFive facts explain why male #breastcancer happens and what changes its outcome. They involve where the first sign shows up, how the disease runs in families, what raises risk and why treatment still borrows from research on women.
@ejhg-journal.bsky.socialSame risk, different access to genetic testing.
📢 A survey across 21 ERN GENTURIS countries shows marked variation in germline testing for #HereditaryCancer 🧬
✨ Harmonised standards and clinical pathways are needed to improve equitable access to genetic diagnostics.
@mburtwrites.bsky.socialIt’s national “previvor” day.
DM me to get the link to the post! And follow @facingourrisk @basserbrca @theprevivor for more information. #BRCA1 #hereditarycancer #cancer #previvor
@doublewhammied.bsky.socialComing from a family of sisters, I very much enjoyed telling the story of these 2 #badass sisters, both diagnosed w/a #BRCA2 mutation that drove their early-stage #breastcancer.
#Hereditarycancer happens, but u can manage yr risk! More info in my @fredhutch.org story. #CanSky #HCAW #knowyourrisk
@gimopenjournal.bsky.socialTelegenetics can help close gaps in cancer genetic care: nearly 90% of local providers joined a collaborative model, highlighting its potential to expand access nationwide. #GIMO #PrimaryCare #Telehealth #HereditaryCancer #GermlineTesting #GeneticTesting
@mburtwrites.bsky.socialLet’s talk about hereditary cancer! Writing about my experience with #brca1 over on Substack today — and I included to a of informative links for you to learn more! —Message me for the link or find it in the replies! #cancer #hereditarycancer
@ejhg-journal.bsky.social📢 A review from the special issue of #EJHG on tumour mutational analysis in #HereditaryCancer: diagnostic, interpretative and therapeutic implications. 🧬
đź”— Read more: www.nature.com/articles/s41...
@gimjournal.bsky.socialContext matters. Phone-based #patientnavigation did not improve genetic service use beyond usual care in a setting with established universal tumor screening—but may still help in lower-access settings. bit.ly/4h97DAQ #CRC #hereditarycancer #genetictesting
@genox-veille.frThis study included females surviving at least 5 years after a childhood cancer diagnosis, from the Childhood Cancer Survivor Study and the St.
@genox-veille.frMSH3 and MLH3 are non-canonical mismatch repair genes that correct insertion-deletion errors. The study analysed about 12,000 colorectal cancer or multiple polyp cases and 460,000 controls, with tumour genome sequencing in 2,023 patients.
@genox-veille.frKEYLYNK-001 is a randomised, double-blind phase 3 trial conducted at 224 centres in 22 countries in patients with stage III-IV epithelial ovarian, primary peritoneal or fallopian tube cancer without a BRCA mutation.
@mygenecounsel.bsky.socialSocial media personality Alix Earle has publicly shared her recent journey with genetic counseling and testing.
Read more about her story here: hubs.li/Q04wQ5n30
#GeneticTesting #GeneticCounseling #BRCA #HereditaryCancer #PrecisionMedicine #EarleMeetsWorld
@jamanetworkopen.com🔬 Among at-risk relatives in families with #HereditaryCancer, a bilingual navigator-supported digital intervention was associated with greater cascade #GeneticTesting completion, informed decision-making, and readiness to pursue testing. ja.ma/4656ANh