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@sigtrans-sttt.bsky.socialSep 11, 2026, 10:12 AM

Can #Disulfidptosis reveal new therapeutic vulnerabilities?

This review examines how NADPH depletion and disulfide stress trigger actin cytoskeleton collapse via the Rac–WRC–Arp2/3 pathway and explores emerging #TherapeuticTargets.

#STTT #OpenAccess: doi.org/10.1038/s413...

Disulfidptosis: molecular mechanisms and therapeutic targets
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