Tenvie Therapeutics initiated Phase 1 first-in-human trials for TNV313, a small molecule NLRP3 inhibitor designed to cross the blood-brain barrier. The company plans to publish preliminary safety and pharmacokinetic data in the first half of 2027.

Tenvie Therapeutics initiated Phase 1 first-in-human trials for TNV313, a small molecule NLRP3 inhibitor designed to cross the blood-brain barrier. The company plans to publish preliminary safety and pharmacokinetic data in the first half of 2027.
"I’m happy to be involved. Even if it does nothing for me, there will be things to be learned for future trials."
75-yr-old Dave Young is the first person in the south to join the SELECTmeso1 #ClinicalTrial which aims to personalise treatment for people with #mesothelioma.
The accepted manuscript of ‘All roads lead to ROAM: A look at the results of the ROAM/EORTC-1308 #ClinicalTrial’ is now available in #NeuroOncology:
JMIR Res Protocols: Feasibility of High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumor and Young Adults With Isocitrate Dehydrogenase–Mutant Gliomas (HYPE): #Protocol for a #RCT #ClinicalTrial
NOW ENROLLING: Led by Aaron Mansfield, MD, of @mayoclinic, a new trial is testing immunotherapy given before surgery for people diagnosed with non-epithelioid or sarcomatoid mesothelioma. Check locations and eligibility at 🔗 https://bit.ly/Alliance-A082101 #CancerCare #ClinicalTrial
Suma Babu, MBBS, MPH, and James Berry, MD, MPH, both past recipients of Next Generation Research Grants (in 2019 and 2013) are leading a #ClinicalTrial of the drug #foralumab to treat #ALS. The first three participants have received their first dose.
SFPT Winter Camp schedule!
20-22nd of January 2027 -Autrans
#SFPT #pharmacology #ClinicalTrial #regulatory #NewDrug #methodology #statistics #robustness #ClinicalPractice #BayesianTest @sfpt-fr.org @claralocher.bsky.social @mcucherat.bsky.social @agnessommet.bsky.social
sfpt-fr.org?view=article...
A surprisingly simple way to relieve knee arthritis pain without pills or surgery #Science #HealthandMedicine #kneehealth #osteoarthritis #clinicaltrial #painrelief #walkingtechnique
Semaglutide causes more lean mass loss (40%) than diet alone (25%), but a new case series shows resistance training + adequate protein may preserve muscle… #Bodycomposition #Clinicaltrial #GLP1agonists #Leanmass #Obesitymanagement #Bodycomposition #Clinicaltrial #GLP1agonists #Leanmass #Obesity…
🔬 New hope for type 1 diabetes: First-in-human trial of immune-engineered cell therapy aims to replace daily insulin injections with a single transplant—… #Celltherapy #Clinicaltrial #Stemcells #Transplantation #Type1diabetes #Celltherapy #Clinicaltrial #Stemcells #Transplantation #Type1diabete…
Researchers are testing a small interfering RNA molecule designed to reduce prion protein production. This marks the first human trial for this treatment.
🔖 JAMA+ Trials is a new platform that highlights the implications and innovations of #ClinicalTrial research from across the JAMA Network to advance evidence-based #medicine and public #health.
📬 Learn more and subscribe to the email newsletter: jamanetwork.com/channels/tri...
#ClinicalTrial Indicates #AI #Chatbots Could Aid Urgent Care
We are now funding a #ClinicalTrial in disorders of consciousness at @casacolina.bsky.social validating an AI drug-disease match led by Dr Caroline Schnakers:
www.cureswithinreach.org/2026/05/28/u...
Using a Diabetic Drug to Restore Awareness to Patients with Reduced Consciousness
#DrugRepurposing
Clinical Trial Finds AI Chatbot Can Help Doctors Prepare for Urgent-Care Visits
🤖 IA: It's not clickbait ✅
👥 Users: It's not clickbait ✅
#aichatbots #urgentcare #clinicaltrial
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👉 Disponible en #risalud hdl.handle.net/10668/29367
JMIR Res Protocols: Game-Based Intervention for Adolescent Pregnancy Prevention: #Protocol for a Multisite #RCT #ClinicalTrial Evaluation
A new randomized trial from the American Heart Association Scientific Sessions (2025) found that tailored vitamin D suppleme… #Cardiovasculardisease #Clinicaltrial #Heartattackprevention #Personalizedmedicine #VitaminD #Cardiovasculardisease #Clinicaltrial #Heartattackprevention #Personalizedme…
New human clinical trial data: Different NAD⁺ precursors follow distinct metabolic routes. Nicotinamide = rapid but transient. NR & NMN = slower, sust… #Clinicaltrial #Microbiome #NADmetabolism #Nicotinamideriboside #Supplementation #Clinicaltrial #Microbiome #NADmetabolism #Nicotinamideribosid…