Depression can amplify Gelsemium elegans neurotoxicity.
CJNM links this effect to disruption of the Clostridium-LCA-PXR-CYP3A11 detox axis.
doi.org/10.1016/S187...
#Depression #Microbiome #Neurotoxicity #CJNM

Depression can amplify Gelsemium elegans neurotoxicity.
CJNM links this effect to disruption of the Clostridium-LCA-PXR-CYP3A11 detox axis.
doi.org/10.1016/S187...
#Depression #Microbiome #Neurotoxicity #CJNM
One enzyme, many natural products!
CJNM identifies PamUGT from Phytolacca americana, a versatile glycosyltransferase for triterpenoids and other compounds.
doi.org/10.1016/S187...
#PamUGT #Glycosylation #NaturalProducts #CJNM
Can an ancient herb help fight kidney fibrosis?
A CJNM review highlights how Rhubarb compounds may act across multiple anti-fibrotic pathways in CKD.
doi.org/10.1016/S187...
#Rhubarb #CKD #RenalFibrosis #NaturalProducts #CJNM
We’re proud to announce that CJNM has been selected for the 2025 Directory of World-Class Scientific and Technological Journals.
CJNM’s latest JCR Impact Factor is 7.5, ranking Q1, 3/48 in Integrative & Complementary Medicine.
Nuciferine, a lotus-leaf alkaloid, targets insulin receptors to combat T2DM-related cognitive decline. It boosts IR/IRS1/IGF-1R, restores PI3K/AKT signaling, reduces yperphosphorylated Tau.