This study shows that #eccDNA-derived circular MIR144 drives age-related #CardiacRemodeling by inducing cardiomyocyte senescence and by promoting interstitial fibrosis and systolic dysfunction in mice.
@sigtrans-sttt.bsky.social
@sigtrans-sttt.bsky.socialThis study shows that #eccDNA-derived circular MIR144 drives age-related #CardiacRemodeling by inducing cardiomyocyte senescence and by promoting interstitial fibrosis and systolic dysfunction in mice.
@physiologyjapan.bsky.social🫀 Just published online in JPS❣️
“Disease-associated myeloid states in cardiac remodeling: A new era of cardiac inflammation research enabled by computational biology”
— Masanori Obana et al.
đź”— doi.org/10.1016/j.jp...
#CardiacRemodeling #CardiacInflammation #ComputationalBiology #JPhysiolSci