#CalcificAorticValveDisease
#Mechanobiology

Side Shear Sex

C-type Natriuretic Peptide (anti-fibrotic protein)
⬆️by 20 dyn/cm2 Cone & Plate Shear (vs 5 dyn/cm2) in ♂️ (not♀️) 🐷valvular endothelial cells

though KLF2⬆️ in both sexes

#JBiomechEng 2026
asmedigitalcollection.asme.org/biomechanica...