An excellent read and also relevant to ML modelling of bioactivity: Srinivasan & Lloyd, Ki Revisited: Principles, Pitfalls, and Best Practices for Measuring Enzyme Inhibitor Affinity. JMC 2026 #biochem #MedChem #cheminformatics #FreeToRead #chemsky 🧪
doi.org/10.1021/acs....

Gehringer & Heppner, In Pursuit of Enduring Inactivation: A Perspective on the Development and Study of Irreversible-Covalent Inhibitors. Biochemistry 2026 #biochem #biophys #MedChem #ChemBiol #OpenAccess #chemsky 🧪
doi.org/10.1021/acs....

Wishing a happy 92nd birthday today to biochemist Mahtab Sohrab Bamji, whose long career was centered around the study of Vitamin B and the biochemistry of its functioning in the body, particularly what happens in Vitamin B deficiency.

#WomenInSTEM #Biochem #NutritionalScience 🧪

🪳 In eusocial insects, queen pheromones help maintain reproductive order within the colony. But where and how these chemical signals are produced can remain difficult to pin down...

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#IOCB #IOCBPrague #czechscience #chemistry #biochem #proteomics

Kartal et al (2021) waveRAPID—A Robust Assay for High-Throughput Kinetic Screens with the Creoptix WAVEsystem. SLAS Discovery 26:995-1003 #biophys #biochem #assay #OpenAccess #chemsky 🧪
doi.org/10.1177/2472...