@transpread.bsky.socialIn Burns & Trauma (September 2026). Funded by NSFC (82302798), the team combined a mouse IR model, scRNA-seq, neutrophil-specific Thbs1 knockout mice, and CD36/JNK modulators to test the THBS1–CD36–JNK axis.
#Neutrophils #Apoptosis,
Details: doi.org/10.1093/burn...
@sciencescandal.com🧬 Your cells die every day.
Sometimes that is not a malfunction. It is the plan. 😳
Why does normal biology need cells to perform an orderly self-destruct, and what happens when they refuse?
@lozanzi.bsky.social#NoTimeToDie! Happy to share my Research Highlight @ Cell Research @natureportfolio.nature.com about a new #necroptosis to #apoptosis axis predicting #IBD relapse recently published @science.org by Murphy &co 👉 www.science.org/doi/10.1126/...
@researchmatters-gl.bsky.social#Throwbackthursday
Episodes from the Archives!!!!
Is methylparaben really safe? Read this article from the 2018 archives.
To know more
researchmatters.in/news/commonl...
Let us know your thoughts and insights!!!
#cosmetics #carcinogens #apoptosis #methylparabens #preservatives #UVexposure
@sigtrans-sttt.bsky.socialCan anti-BCL2 therapy achieve durable clearance of giant congenital melanocytic nevus?
BCL2 inhibition targets senescent and proliferative cells while inducing neutrophil extracellular traps and T-cell responses.
STTT #OpenAccess: doi.org/10.1038/s413...
#Apoptosis #CancerTherapy
@sigtrans-sttt.bsky.socialPARP inhibitor resistance reflects a balance between #Apoptosis and persistent #Senescence in #OvarianCancer. This study identifies BCLXL blockade as a strategy to restore apoptotic vulnerability and enhance PARPi response.
@vaccinologist.bsky.socialWe used to learn that #cells mainly die by #apoptosis or #necrosis. Today, scientists describe 20+ forms/pathways of #celldeath, from pyroptosis and ferroptosis to necroptosis, cuproptosis and disulfidptosis. #Cellbiology has changed enormously. lnkd.in/p/e-6ew_i8
@currentmedscience.bsky.socialThis study demonstrates that #CHOP deficiency intensifies inflammation, epithelial #apoptosis, and injury in OAB mice by suppressing #ERStress, pointing to CHOP as a therapeutic axis. #medsky
Read more: doi.org/10.1007/s115...
@antibodytx.bsky.socialAntibody Therapeutics (IF=4.8, Oxford University Press) ⚡ Review Highlight -Beyond ADCs: harnessing bispecific antibodies to directly induce apoptosis for targeted tumor eradication.
doi.org/10.1093/abt/...
#bispecific #bispecificantibody #bsab #bsabs #apoptosis #deathreceptor5
@sigtrans-sttt.bsky.socialHow does #METTL3 drive pancreatic acinar cell carcinoma?
Researchers show that #RNAmethylation promotes tumor growth via m⁶A-dependent tumor programs and stromal crosstalk, while its inhibition triggers #Apoptosis.
@blametheamygdala.comIn the blood brain barrier, an #astrocyte conspired with a platelet to destroy all #neurons. Betrayed by a #macrophage posing as a microglia trying to pickup the #EpsteinBarrVirus, it was sentenced to #apoptosis. The astrocyte was paroled and now sells used sodium to neurons. #neuroscience #stories