🔔 Hot article by Pei-Qiang Huang 𝘦𝘵 𝘢𝘭.
Reductive alkenylation of tertiary amides with alkenylchlorozirconocenes and alkenylboronic acids: a new approach to α-branched (E)-allylic amines

🔔 Hot article by Pei-Qiang Huang 𝘦𝘵 𝘢𝘭.
Reductive alkenylation of tertiary amides with alkenylchlorozirconocenes and alkenylboronic acids: a new approach to α-branched (E)-allylic amines
How can #cobalt #catalysis enable the asymmetric synthesis of challenging chiral #amides? Wenyu Zhao & Yifeng Chen report a cobalt-catalyzed asymmetric carbamoyl addition to imines, giving α,α-disubstituted α-amino amides with excellent enantioselectivity✨