@abseabio.bsky.socialA good α-syn antibody pair on recombinant protein may behave differently in biological samples.
P2P2P™ tests candidate pairs beyond standard protein, including in complex samples.
8 α-syn pairs are now available, validated across both.
@stressmarq.bsky.socialProduct Citation: Histopathological analyses revealed extensive pSer129-αSyn+ neuritic inclusions in a mouse model of #Parkinson's disease, post-injection with StressMarq's Mouse #AlphaSynuclein PFFs.
Paper 💻 https://bit.ly/4f439dh
Product details 🐭 https://bit.ly/2HJyYee
@gmj-georgia.bsky.social🧠 Major breakthrough: Yale scientists identified two neuron surface proteins that control how the toxic protein alpha-synuclein spreads i… #Alphasynuclein #Neurodegenerativedisease #Neuroinflammation #Parkinsonsdisease #Yaleneuroscience #Alphasynuclein #Neurodegenerativedisease #Neuroinflammati…
@rpeptide.bsky.socialThe Alpha-Synuclein used in this study is available from rPeptide!
Our Synuclein product line includes native and mutant sequences, labeled options, fragments, and preformed fibrils to support a wide range of studies. 🔬
@rpeptide.bsky.socialCould naturally occurring antibodies hold the key to treating Parkinson's Disease?
Research shows autoantibodies targeting Alpha-Synuclein's NAC region can block toxic aggregation, studied using rPeptide's ASyn and defined fragments. 🧠
@gmj-georgia.bsky.socialTGen researchers at City of Hope have uncovered a protein cascade mechanism where amyloid-beta plaques trigger tau and alpha-synuclein accumulatio… #Alphasynuclein #Alzheimers #Amyloidbeta #Mixedpathology #Neurodegeneration #Alphasynuclein #Alzheimers #Amyloidbeta #Mixedpathology #Neurodegenera…
@molneurodegenadvnc.bsky.socialAs part of our inaugural review series!
Targeting protein aggregate co-pathologies in #neurodegeneration: a viable therapeutic strategy?
Silas A. Buck, Sidharth S. Madhavan, Laurie H. Sanders
@dukemedschool.bsky.social #TDP43 #tauopathy #amyloid #alphasynuclein
@gmj-georgia.bsky.socialBreakthrough at Baylor: tubulin can redirect toxic brain proteins away from harmful clumps in Alzheimer's an… #Alphasynuclein #Alzheimersdisease #BaylorCollegeofMedicine #Neurodegenerativedisease #Neurologicalresearch #Alphasynuclein #Alzheimersdisease #BaylorCollegeofMedicine #Neurodegenerativ…
@molneurodegenadvnc.bsky.socialSpreading #alphasynuclein #oligomers trigger #astrocyte/ #microglial changes and astrocyte-glutamatergic neuron system dysfunction in an age-related manner
Jaehyun LeeBae, Verena Bopp, Alicia Goreth...Karin M. Danzer #Parkinsons
@sjorsscheres.bsky.socialMichel Goedert and myself are looking for two postdocs to work on #cryoEM and #masspec of #alphasynuclein filaments from neurodegenerative disease. Come join our bubbly and friendly team at the @mrclmb.ac.uk in lovely Cambridge, UK.
@gmj-georgia.bsky.socialBreakthrough at Baylor: tubulin can redirect toxic brain proteins away from harmful clumps in Alzheimer's an… #Alphasynuclein #Alzheimersdisease #BaylorCollegeofMedicine #Neurodegenerativedisease #Neurologicalresearch #Alphasynuclein #Alzheimersdisease #BaylorCollegeofMedicine #Neurodegenerativ…