Kaempferol attenuates type 2 diabetic osteoporosis via METTL3/YTHDF2-regulated PTEN m⁶A methylation and ferritinophagy-ferroptosis inhibition

Pharmacological research · Huang et al.
doi.org/10.1016/j.phrs.2026.108473
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m6A mRNA methylation regulates pancreatic α-cell plasticity

Nature metabolism · De et al.
doi.org/10.1038/s42255-026-01591-z
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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Molecular medicine reports · Guo et al.
doi.org/10.3892/mmr.2026.14025
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Phosphate backbone epitranscriptomics: Discovery of natural RNA phosphorothioates and their writer machinery

Cell · Maman et al.
doi.org/10.1016/j.cell.2026.08.034
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METTL3 mitigates age-related hearing loss by inhibiting NF-κB-mediated inflammatory responses through the m6A modification of NFKBIA

Journal of molecular medicine (Berlin, Germany) · Tan et al.
doi.org/10.1007/s00109-026-02714-5
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Regulation and function of the HPV16 CircE7 RNA

Journal of virology · Lee et al.
doi.org/10.1128/jvi.01284-26
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RBM15 Contributes to Bladder Carcinoma Progression via m6A-dependent Stabilization of IFI6 mRNA

Applied biochemistry and biotechnology · Zhang et al.
doi.org/10.1007/s12010-026-05924-2
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Dynamic reprogramming and A-to-I RNA editing in neutrophils in response to tumor induction

The Journal of biological chemistry · Cao et al.
doi.org/10.1016/j.jbc.2026.113569
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RNA demethylase FTO uses conserved aromatic residues to recognize the mRNA 5' cap and promote efficient m6Am demethylation

The Journal of biological chemistry · Shimanski et al.
doi.org/10.1016/j.jbc.2026.113573
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Polystyrene microplastic uptake drives Inflammatory, Epitranscriptomic, and Metabolic Reprogramming in Human Aortic Endothelial cells

Environmental pollution (Barking, Essex : 1987) · Khan et al.
doi.org/10.1016/j.envpol.2026.129187
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Transcript-wide m6A methylation defines the efficiency of cap-independent translation initiation

RNA (New York, N.Y.) · Smolin et al.
doi.org/10.1261/rna.081017.126
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MiR-662 impairs C/D box snoRNA expression and rRNA 2'-O-ribose methylation marks

BJC reports · Filossi et al.
doi.org/10.1038/s44276-026-00247-5
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Sublethal heat stress-induced HSF4 upregulation via GRSF1 in an m6A-dependent manner in hepatocellular carcinoma

Chinese medical journal · Chen et al.
doi.org/10.1097/cm9.0000000000004188
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Oscillatory shear stress-induced endothelial extracellular vesicles exacerbate aortic valve calcification

Cardiovascular research · Chen et al.
doi.org/10.1093/cvr/cvag205
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Accurate imaging of m6A on specific mRNA with proximity ligation-triggered RCA-FISH (PLTRF-m6A)

Chemical communications (Cambridge, England) · Cao et al.
doi.org/10.1039/d6cc04660f
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FTO-mediated GPX4 m6A modification in ferroptosis-induced DNA damage and inflammatory response during acute lung injury

Journal of bioenergetics and biomembranes · Liu et al.
doi.org/10.1007/s10863-026-10133-x
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Allosteric modulation of YTHDFs by ellagic acid suppresses triple-negative breast cancer via non-canonical activation of the HIF-1α pathway

Cell reports. Medicine · Zhou et al.
doi.org/10.1016/j.xcrm.2026.103045
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Targeting IGF2BP3-driven CSF1/CSF1R signaling disrupts the positive feedback loop between tumor cells and macrophages and inhibits HCC progression

Life sciences · Ji et al.
doi.org/10.1016/j.lfs.2026.124681
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METTL7B attenuates pathological cardiac hypertrophy via m6A-associated regulation of HK3

Molecular and cellular biochemistry · Bao et al.
doi.org/10.1007/s11010-026-05737-1
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Structure-guided identification and experimental validation of NAT10-targeting small molecules in colorectal cancer cells

Journal of computer-aided molecular design · Xu et al.
doi.org/10.1007/s10822-026-00890-7
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