@scienceofpd.bsky.socialThe EJS ACT PD consortium presents the patient-centric development of an inclusive multi-arm multi-stage trial for #Parkinsons; Highlighting 5 challenges (& solutions) that were confronted - a monumental effort!
academic.oup.com/braincomms/a...
@scienceofpd.bsky.socialNew data suggests that α-Synuclein seeding discriminates between LRRK2 G2019S variant carriers with & without #Parkinsons; N = 76 variant carriers (N = 22 with PD, N = 54 w/o); Seeding observed in 80% with LRRK2-PD & in 1 unaffected carrier
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
@scienceofpd.bsky.socialResearchers present the HandPD37 dataset, including handwriting samples from 78 #Parkinsons case & 54 healthy controls across 37 tasks, tailored for Japanese participants, enhancing the dataset’s applicability for more accurate & generalized PD detection
www.nature.com/articles/s41...
@scienceofpd.bsky.socialWow! 20 years of induced pluripotent stem cells...
New review explores how "the field has progressed from patient-specific disease modeling toward cell-based therapies for neurodegenerative disorders" (#Parkinsons gets highlighted)
Man, I feel old...
www.cell.com/cell-reports...
@scienceofpd.bsky.socialResearchers report that Fejerin, a peptide isolated from frog skin mucus, protective effects in both in vivo & in vitro models of #Parkinsons (via the PINK1-Parkin pathway)
www.nature.com/articles/s42...
@scienceofpd.bsky.socialRecent studies have reported that α-synuclein undergoes phase separation to form biomolecular condensates. Now researchers find that specific #Parkinsons-associated α-synuclein variants (A30G, G51D, & A53E) fail to form them, while E46K & E83Q enhance them
www.nature.com/articles/s41...
@oldmanrambling.bsky.socialCut Tulips are back in the shops, reminding me that I need to plant bulbs to flower in April for Parkinson's Awareness Month, the disease that ate my lovely wife's mind.
#ColorADay #PinkMon
#Tulips #Flowers #Parkinsons #ForJanet
#Bloomscrolling #ECK
#PhotographersOfBluesky
#iPhonePhotography
@researchmatters-gl.bsky.socialResearchers at CSIR-CIMAP and AcSIR have used machine learning to identify biomarkers of Parkinson's disorder.
To deep dive, tap
researchmatters.in/news/machine...
#Parkinsons #fruitflies #AI #machinelearning #scienceeducation #scicomm #Indianscience #sciencecommunication
@togetherforsharon.bsky.social🎬 PLEASE WATCH “SHARON’S STORY” ❤️
We WON’T REST until the world is aware. If you’re battling Parkinson’s, YOU ARE NOT ALONE.
WATCH. SHARE. Help us reach more people.
For Sharon. For every family. Until there is a cure.
@worldpdcongress.bsky.socialCould you be a WPC Parkinson Ambassador? 💜 Apply for WPC 2029 in Québec City by November 5! #Parkinsons #WorldParkinsonCongress
@braincomms.bsky.socialTheofanopoulou et al. report that resting state functional MRI in Parkinson’s disease, shows both increased and decreased connectivity across movement-related brain regions, with some of these alterations being linked to disease burden.
Read it at 👉https://buff.ly/zEvFKpZ
@stroudarian.bsky.socialTHIS is the news we need!
Michael J. Fox was invested as a Companion of the Order of Canada, honouring his extraordinary advocacy for people living with Parkinson’s.
He gave us unforgettable characters. He keeps giving people hope.🇨🇦🍁♥️🤍
@togetherforsharon.bsky.social🎬 PLEASE WATCH SHARON’S STORY
▶️ WATCH youtu.be/RkWTMNFmUdM
⭐ Review on IMDb: www.imdb.com/title/tt4765...
Please WATCH. SHARE. Help me reach people who need to know:
💜 NO ONE IS EVER ALONE.
For every family. Until there is a cure.
#SharonStory #TogetherForSharon #Parkinsons #ParkinsonsAwareness
@scienceofpd.bsky.socialUsing a novel autoantibody screening platform developed by Sengenics, researchers conducted a 2-stage case-control study to identify peripheral autoantibodies in #Parkinsons that may be useful as potential diagnostic markers
www.nature.com/articles/s41...
@scienceofpd.bsky.socialNew research suggests that "skin denervation is closely associated with cognitive impairment in #Parkinsons & that regional brain atrophy statistically mediates this relationship"; N=155 patients with PD (PD-NC = 75; PD-MCI = 40; PDD = 40) & 50 controls
www.neurology.org/doi/10.1212/...
@parkinsonseurope.bsky.socialWe'll be there! Secure your free place today: buff.ly/fqZyPnO
@parkinsons.org.uk #ParkinsonsUK #ParCon #Parkinsons
@scienceofpd.bsky.socialIn GBA- #Parkinsons, subthalamic nucleus-deep brain stimulation treatment at later stages is associated with⬆️risk of cognitive decline. Earlier STN-DBS in GBA-PD may extend the period of improved motor function before onset of cog. decline
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
