#Petrelintide is a novel, long-acting #amylin analogue being developed for long-term treatment of #obesity, leveraging a mechanism of action distinct from incretin-based treatments thelancet.com/journals/lan...
#FREE to read w/reg (also FREE)

#MedSky #EndoSky

Epstein survivor Laura Bloom McGee: “Then it takes that hunger (for attention) and turns it into a leash… This is about monsters and victims.”

fb.watch/v/5aoxFzde1/... #BlueSky #MedSky #LawSky #press #Epstein #EpsteinSurvivors #MeToo #SurvivorVoices #Accountability #JusticeForVictims

#Medsky🧪 #IDsky #microsky #publichealth @nature.com
Although the risk of a wider epidemic is minimal .The #Yersiniapestisbacterium that causes the disease is treatable with #antibiotics . The incident exposes vulnerabilities in global biosurveillance
www.nature.com/articles/d41...

Can obesity ever be protective in older adults?

This study explores the relationship between sarcopenia, sarcopenic obesity, functional dependence, malnutrition and mortality in older adults, highlighting the complex concept of the obesity paradox.

🔗 bit.ly/479uMP8
#MedSky #GeriSky #GeroSky

Shukri F Mohameda & Andre Pascal Kengne comment on:
What #Mauritius teaches us about #diabetes #surveillance thelancet.com/journals/lan...
#T2D #prevalence #OGTT
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#MedSky #EndoSky

#Mauritius is the first country to show a decreasing prevalence of type 2 #diabetes and intermediate hyperglycaemia over time, using the objective, gold standard #OGTT-based diagnostic criteria recommended by the WHO thelancet.com/journals/lan...
#FREE to read w/reg (also FREE)

#MedSky #EndoSky

and has spent or pledged
more than $400 million to get 31 countries to take them.

Officials appear to see the mistreatment as a feature, not a bug. Reagan signed the Convention Against Torture and the Senate ratified it. At minimum, honor it.

#BlueSky #MedSky #LawSky

Study finds restoring cortical disinhibition reduces Huntington's symptoms. In-depth 2-photon imaging reveals roles of neuronal subtypes. HD movement disorder unravelled. PMID:42386967, Nature 2026, @Nature https://doi.org/10.1038/s41586-026-10671-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A simple metabolic marker may signal heart risk.

This study links greater #InsulinResistance to a higher 10-year risk of #CardiovascularDisease, highlighting metabolic health as an important predictor of future heart events.

#currentmedicalscience: doi.org/10.1007/s115...
#medsky

Published in @ebiomedicine.bsky.social

A proteome-based classification of paediatric #adrenocortical #tumours links functional tumour states to clinical outcome and therapeutic vulnerabilities www.thelancet.com/journals/ebi...
#OpenAccess

#MedSky #EndoSky

Developed a CRISPR knockout mouse library targeting 84 host genes for in vivo influenza A studies, paving the way for better understanding of viral pathogenesis. PMID:42302780, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600591X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

#Medsky🧪 #IDsky #publichealth #Vaccinesmatter The emerging #COVID sub-variant PJ.2.1 is a highly mutated strain first detected in May 2026 that has achieved rapid intercontinental spread.

A phytoscreen of 43 fruits and veggies reveals garlic as a strong deterrent of mating and egg-laying in Drosophila. Diallyl disulfide, a garlic compound, inhibits both behaviors! PMID:41999745, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00338-7 #Medsky #Pharmsky #RNA #ASHG 🧪

#Medsky🧪 When results fail to replicate, researchers often scrutinize the #biology first, but overlooked technical variables can also add costly and avoidable variation.

www.the-scientist.com/when-biology...

#Medsky🧪 #IDsky #publichealth Evaluated the impact of #COVID, #Malaria, and their co-infection on hemostatic parameters, specifically looking at Platelet Distribution Width (PDW) and D-dimer levels through a sex-stratified lens
@plosglobalpublichealth.org
journals.plos.org/globalpublic...

Prion-based switching of DNA repair proteins in Saccharomyces cerevisiae boosts mutagenesis rates, enabling rapid adaptation in diverse environments. Fascinating evolution insights! PMID:42263676, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00577-5 #Medsky #Pharmsky #RNA 🧪

Targeted TFO liposome (tLipo-TFO1) reduces PAI-1, addressing pulmonary fibrosis by enhancing ECM clearance. PMID:42385711, Cell Rep Med 2026 https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00326-5?rss=yes&utm_source=dlvr.it&utm_medium=twitter #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Healthy life line: Relax and unwind as you read the best books you can find. Healthy Life Lines amzn.to/3goUC6Y #health #NationalBookMonth #books #BookSky #HealthSky #MedSky #HealthLiteracyMonth #readers #authors

Metastasis in CRC is driven by tumor cell plasticity. TROP2, a marker linked to poor outcomes, associates with WNT^low and fetal-like states, fueling resistance. PMID:42386981, Nature 2026, @Nature https://doi.org/10.1038/s41586-026-10705-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪