Med News: Drs Emmanuel Mignot and Masashi Yanagisawa, winners of this year’s @laskerfdn.bsky.social Basic Medical Research Award, discuss how their research on the neuropeptide orexin led to a new #narcolepsy treatment💤

Med News: Drs Emmanuel Mignot and Masashi Yanagisawa, winners of this year’s @laskerfdn.bsky.social Basic Medical Research Award, discuss how their research on the neuropeptide orexin led to a new #narcolepsy treatment💤
“Hollywood can be daunting, but it has nothing on the biomedical research enterprise. We plunged headfirst into a system we knew nothing about,” 2026 Public Service #LaskerAward winner Michael J. Fox writes for @JAMA.com.
“Biology defined the required function, pharmacology defined the appropriate balance, engineering made the molecule manufacturable, & persistent optimization converted an unconventional idea into a novel therapeutic,” 2026 #LaskerAward winners Hattori, Kitazawa, and Igawa write in @JAMA.com. 🧪
Emmanuel Mignot & Masashi Yanagisawa receive a 2026 #LaskerAward for discoveries linking orexin, wakefulness & narcolepsy. Read the Proceedings of the National Academy of Sciences Perspective: https://ow.ly/7TUm50ZM2ij
#Lasker2026 #LaskerLaureate Albert and Mary Lasker Foundation
“Two convergent approaches from our respective laboratories identified the orexin system as an essential wake-promoting, REM-inhibiting neurotransmitter—work now yielding new hypnotics and, more excitingly, new wake-promoting drugs,” 2026 #LaskerAward winners Mignot & Yanagisawa write in @JAMA.com.🧪
Joseph L. Goldstein shared a 1985 #LaskerAward & #NobelPrize with Michael Brown for the discovery of the basic mechanisms controlling cholesterol metabolism. Today, Goldstein is Lasker Jury Chair & writes an annual essay on the art of science to accompany the announcement of the Lasker Awards. 🧪
The 2026 Public Service #LaskerAward honors Michael J. Fox for empowering patients’ voices and accelerating research to find improved therapies and a cure for #ParkinsonsDisease.
🧪 Fox and his Foundation have helped dispel stigma and spearhead a revolution in PD research: https://ow.ly/Yt3l50ZLArE
#Hemophilia A Treatment Pioneers Win #LaskerAward
#Immunology #Science
#Hemophilia A Treatment Pioneers Win #LaskerAward
#Immunology #Science
The 2026 Clinical Medical Research #LaskerAward honors Kunihiro Hattori, Takehisa Kitazawa, and Tomoyuki Igawa for their invention of a bispecific antibody that treats hemophilia A by preventing uncontrolled bleeding. Read how their antibody works: https://ow.ly/2Psi50ZLAfB
The 2026 Basic Medical Research #LaskerAward honors Emmanuel Mignot and Masashi Yanagisawa for discovering orexin, a brain peptide that maintains wakefulness, and for showing that its absence causes narcolepsy. Learn more: https://ow.ly/I1V450ZLA1p
#Lasker2026 Stanford Medicine 🧪
“More than a decade of work led to a dual-targeting antibody mimic of a blood clotting protein to treat hemophilia A. Three scientists received a #LaskerAward for their efforts,” The Scientist reports.
Michael J. Fox received a #LaskerAward for his work fighting Parkinson’s disease. “[I knew] my name could attract attention to help us achieve our goals faster. I also have this disease. I know the issues & I share my community’s sense of urgency,” Fox told People Magazine in an exclusive article. 🧪
Two researchers, Emmanuel Mignot and Masashi Yanagisawa, have won the prestigious Albert Lasker Basic Medical Research Award. “Their findings laid the groundwork for a new drug that addresses [narcolepsy’s] root cause,” The New York Times reports.
“Their collective research efforts demonstrate how imagination, determination, & multidisciplinary scientific research come together to improve patients’ lives,” William Pao writes of the Clinical Medical Research Lasker Award winners in
@pnas.org. 🧪
🧪 @pnas.org has partnered with Lasker to celebrate each year’s award winners, bringing you written perspectives. From these, you’ll learn about the inspiring history and significance of the 2026 #LaskerAward winners’ work.
Want to learn more about our six #LaskerAward winners Emmanuel Mignot, Masashi Yanagisawa, Kunihiro Hattori, Tomoyuki Igawa, Takehisa Kitazawa, and Michael J. Fox? Visit our website at www.laskerfoundation.org.
Celebrating the 2026 #LaskerAward honorees! 🏅
Basic Medical: Emmanuel Mignot & Masashi Yanagisawa
Clinical Medical: Kunihiro Hattori, Tomoyuki Igawa & Takehisa Kitazawa
Public Service: Michael J. Fox
Explore now:
https://ow.ly/LTLw50ZKNse
#LaskerLaureate Albert and Mary Lasker Foundation
Honoring scientific excellence with the 2026 #LaskerAward! 🏅
Basic Medical: Emmanuel Mignot & Masashi Yanagisawa
Clinical Medical: Kunihiro Hattori, Tomoyuki Igawa, and Takehisa Kitazawa
Public Service: Michael J. Fox
Explore now:
https://ow.ly/zmPq50ZKNt2
#LaskerLaureate #LaskerFDN
How does the brain peptide orexin maintain wakefulness?
🧪In an astounding experimental intersection, Emmanuel Mignot of Stanford Medicine and Masashi Yanagisawa of the University of Tsukuba revealed a key insight into the nature of sleep.