Did you know carbohydrates can modify 10 of the 20 amino acids, from GlcNAc-Tyr in tumor cells to Glc-Arg in bacterial signaling?

Find out about more: research.bidmc.org/ncfg/blog/30...

#glycobiology #biochemistry #proteomics #posttranslationalmodification #cellbiology #glycotime

Human NEU3 and NEU4 enzymes prefer short polysialic acid substrates
#glycotime #CarbohydrateResearch

Finding granule-bound starch synthase enzymes with high activity using free-energy calculations
#glycotime #CarbohydrateResearch

🚨New GlycoPOST dataset - GPST000735🚨
N-glycans of Xenopus brain
PI: Shunji Natsuka
#glycotime #glycoPOST

Evaluation of acylated/deacylated ghrelin, CCL20/CCR6 concentration, and IgG N-Glycan alterations in different dysplasia grades of colon adenoma
#glycotime #GlycoconjugateJournal

Synthesis of chitooligosaccharide selenol derivatives by homogeneous dissolution in dipolar aprotic/lithium salt solvents
#glycotime #CarbohydrateResearch

How to study glycosylation using bioorthogonal glycan-based tools: now in one comprehensive review. Highly recommended!

tinyurl.com/27z2rhvv

#glycotime

Click Chemistry Enabled Glyco-Macrocycles,
#glycotime #CarbohydrateResearch

A 4-Trehalosamine-Derived Acrylamide Monomer: Synthesis and Preparation of Composition-Tunable Water-Soluble Polyacrylamides
#glycotime #CarbohydrateResearch

Dynamic inter-glycan interactions regulate site-specific N-glycan maturation in human Fcγ receptor III
#glycotime #Glycobiology

Synthesis of L-iduronic acid Containing a Common Pentasaccharide Repeating Unit Related to <em>Escherichia coli</em> O112ab and <em>Shigella boydii</em> serotype B15
#glycotime #CarbohydrateResearch

Box-Behnken design optimization of ulvan extraction from <em>Ulva lactuca</em>: <em>in silico</em> and <em>in vitro</em> biological activities
#glycotime #CarbohydrateResearch

Polysaccharides from <em>Poria Cocos</em> alleviate adenine-induced chronic renal injury via improving gut microbiota disorder
#glycotime #CarbohydrateResearch

Synthesis of the Endogenous Non-Reducing End Heparan Sulfate Disaccharides for Newborn Screening and Diagnosis of Mucopolysaccharidosis types I and II
#glycotime #CarbohydrateResearch

First Total Synthesis of Capsicoside C2 through Regio- and Stereoselective Linear Glycan Assembly
#glycotime #CarbohydrateResearch

(NB. we also describe a convenient approach for tracking HA degradation by solution 1H NMR, where labeling with 13C is not needed - compare to our recent work on 13C labeling HA)

#glycotime #hyaluronan

A new preprint from my lab - this time on chemRxiv: Xingang Liu et al "Unmasking the Non-Covalent Nature of HA–Dopamine Assemblies: Insights from 1H NMR Degradation Tracking and Multidimensional NMR”

Notably, my lab’s first solution #NMR paper !!

#nmrchat #glycotime

doi.org/10.26434/che...

Super amazing #glycotime ⬇️😎

📅 Mark your calendars for the 2027 Gordon Research Conference on Glycobiology!

🗓️ March 14–19, 2027
📍 Ventura, California

🧬 BioF:GREAT is a proud sponsor & Dr. Lance [email protected] is co-chairing the conference!

www.grc.org/glycobiology...

#NSF #biofgreat #glycotime

This presents the first incorporation of our Chemical Precision Tools in a transgenic model system 🤩. A fantastic collaboration with colleagues including JP Vincent, Kelly Ten Hagen and Nadine Samara, and building on great precedent by David Vocadlo and Xing Chen. #glycotime