Leendert mentions synthetic microorganisms created with a minimal number of genes, based on knowing the function of the genes. For the reduced genome Bacillus subtilis, still 22% of the genes are unknown functions. How to identify their functions, especially in case of redundancy?

#EMBOBacNet

Leendert Hamoen on Facilitating Functional Characterization Of Y-Genes
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Entertaining talk by Bavesh Kana for Science & Society session at #EMBOBacNet on What We Cannot Count, We Cannot Cure: Hidden Tuberculosis and the Limits of Diagnosis

Cool story on the origin of ICE element activation double bistability in Streptococcus

Superb work by Milena Jaskólska, Jesús Cámara-Almirón, and Aurora Zhou

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Last time I heard Jan Willem giving lecture (at KNVM meeting), he had Mandalorian quote (if I correctly remember), now Stargate video in his talk how Goa’uld transfer in comparison to ICE element transfer

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Jan Willem Venning @veeninglab.com on Stacked bistable regulation of widespread Streptococcal ICEs conferring MDR

@dmf-unil.bsky.social

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Work from Dolan lab @stephenkdolan.bsky.social

See their previous PNAS paper as teaser: www.pnas.org/doi/10.1073/...

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Jessica Aycock on A conserved bacterial regulatory network enables bacterial adaptation to fungal-derived disulfide toxins

Pseudomonas aeruginosa and Aspergillus fumigatus, yay for BFI!
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Cristina Colomer-Winter @colomer-winter.bsky.social (from the lab of @kimingeneva.bsky.social) on A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin

LiaR in Enterococcus

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See their bioRxiv on the two different proteases
www.biorxiv.org/content/10.6...

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Kristina now switches to Pseudomonas Lon protease and Lon-like protease, AsrA, where Lon proteases are also important for motility and other phenotypes, in addition to revealing new Lon protease target proteins

See their PLoS Pathogens paper journals.plos.org/plospathogen...

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Kristina Jonas @krijonas.bsky.social starts #EMBOBacNet today with a talk on Lon-mediated proteolysis in bacterial pathogenicity and stress adaptation

Morning run before another day of #EMBOBacNet conference

Anthony finishes with inviting all to next year GRC Cell Biology and Development conference that he chairs together with @krijonas.bsky.social June 6-11 in Southern New Hampshire University including an amazing list of invited speakers (see photo), more info
www.grc.org/bacterial-ce...

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Anthony highlights the available positions in their group, contact via BlueSky or email for post doc position
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Anthony explains the work of Y Hoang including cool structural insights onto carboxysomes
See their bioRxiv (accepted for publication an hour ago👏): www.biorxiv.org/content/10.1...

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Anthony on carboxysomes (sole source of carbon from growth) organization is Synechococcus elongatus, the role of McdA

See their @elife.bsky.social paper elifesciences.org/articles/39723
And also bioRxiv www.biorxiv.org/content/10.1...

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Anthony Vecchiarelli @cellforganized.bsky.social presents: Yes! Bacteria have organelles! How are they organized?
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Mariana Gomes de Pinho on Chromosome Segregation Dynamics During the Cell Cycle of Staphylococcus aureus

Coming soon in @natmicrobiol.nature.com

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Martin on finding ParB paralogs, eg.VirB from Shigella flexneri

See their @natcomms.nature.com
www.nature.com/articles/s41...

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