PBM execs swore under oath they pass through 100% of rebates.
The next day, CVS settled for $43M.

That's transparency washing. Joe Shields of Transparency Rising scrubs it clean on a new PBM on the Rocks.

Episode Drops Tomorrow! ⏰
#PBMreform #IndependentPharmacy #PBMOTR #PharmSky

Key findings reveal that MBS1, a mediator of 1O2 responses, forms protein condensates in chloroplasts, enhancing high-light tolerance and protecting against photodamage. PMID:42309053, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00642-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

3D diffusion autoencoders analyze cardiac MRI data from 71,017 UK Biobank participants, unveiling reproducible, heritable phenotypes (h² = 4–18%). Fascinating insights! PMID:42373625, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74575-y #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Revolutionizing embryonic research: Primates' organogenetic embryoids from cTBLCs showcase totipotent features, advancing models from zygote to early organogenesis. PMID:42269606, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00582-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A 14-protein plasma signature predicts lung cancer risk >5 years before diagnosis, enhancing prevention strategies beyond IL-1β inhibition's high NNT. PMID:42242224, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Exploring >20 neuronal autoantibodies in diagnosing autoimmune encephalitis can transform treatment approaches. Discuss! 🔍🧠 PMID:42371614, JAMA Neurol 2026, @JAMANeuro https://doi.org/10.1001/jamaneurol.2026.2027 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Systematic CRISPR screens in human CD4+ T cells found 43 pro- and 91 anti-HIV host factors, unveiling diverse antiviral mechanisms and potential therapeutic targets. PMID:42013838, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600382X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

The cGAS-STING pathway detects dsDNA, linking innate immunity to tissue homeostasis and antitumor activity. Its role in inflammation opens new therapeutic avenues. PMID:42349382, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00650-1 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New research identifies MARCH7 as a key E3 ubiquitin ligase that regulates intracellular iron, acting as a dual suppressor of ferroptosis by ubiquitylating NCOA4. PMID:42049018, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00388-0 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

3'-UTR variants influence mRNA regulation, impacting alcohol use disorder risk. #GeneticsInFocus PMID:42374457, Genome Biol 2026 @OTSociety @NAR_Open https://doi.org/10.1186/s13059-026-04176-x #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Today is the LAST DAY to apply to bring SURF to your institution, and help introduce undergraduate students to pharmacology research.

Learn more and apply: https://ow.ly/xT5k50ZQjMr

#pharmsky 🧪

Today is the LAST DAY to apply to bring SURF to your institution, and help introduce undergraduate students to pharmacology research.

Learn more and apply: https://ow.ly/xT5k50ZQjMr

#pharmsky 🧪

Frequent prion-based switches in DNA repair proteins drive adaptive mutagenesis in Saccharomyces cerevisiae, enhancing evolution across diverse environments. PMID:42263676, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00577-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Heat stress boosts susceptibility to metabolic dysfunction when followed by an obesogenic diet in mice, driven by KLK14's impact on hypothalamic LRRC7⁺ astrocytes. PMID:42019490, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00346-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A study reveals >1,000 molecular changes in SOD1-G93A mouse motor neurons, leading to a new "disease-associated motor neuron" state, key to ALS progression. PMID:42335888, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00647-1 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A novel screening platform using 84 CRISPR-Cas9 mouse lines targets host factors crucial for understanding influenza A virus. This boosts in vivo functional validation! PMID:42302780, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600591X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A phytoscreen of 43 fruits/vegetables revealed garlic as a key deterrent of mating and egg laying in Drosophila and mosquitoes. Diallyl disulfide disrupts these behaviors! 🍏🦟 PMID:41999745, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00338-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New paleoproteomic analysis of 23 H. naledi dental enamel specimens from 20 individuals reveals no male markers, suggesting a single-sex sample in a unique population. PMID:42341758, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00644-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Unlocking myxobacteria: New genetic tools and a heterologous chassis boost bioactive compound discovery. MxRecET recombinases enhance genome editing in Myxococcus xanthus DK1622. PMID:42373632, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74908-x #Medsky #Pharmsky #RNA #ASHG 🧪

Arabidopsis seeds pack histone variant H2B.8, arranging 3D nuclear space. Upon imbibition, H2B.8 is evicted, hinting at chromatin reprogramming in seed-to-seedling transition! PMID:42373623, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74230-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪