A benchmark shows that sequence-search tool choice changes recall, runtime and resource use in #CRISPR spacer–protospacer detection. Bowtie1 with ≤3 mismatches offers a practical balance for large-scale host–MGE analyses 🧬
📄 https://doi.org/10.1093/bioinformatics/btag394
👤 EVBC: Uri Neri, Simon Roux
